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Results of isolated limb perfusion for metastasized malignant melanoma.

Author: ErdmannMichael, FoertschThomas, FrengerJohannes, GoehlJonas, GruetzmannRobert, KerstingStephan, MerkelSusanne, SchellererVera S

Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.

Overview

This study analyzed the results of hyperthermic isolated limb perfusion (HILP) in 80 patients with locoregional metastases of the extremities. HILP was effective in achieving remission, with a high response rate. The median overall survival rate was 33 months.
Paper Details　
Original Abstract of the Article :
BACKGROUND AND OBJECTIVES: Locoregional metastases are typical biological manifestations of advanced malignant melanomas. Treatment with hyperthermic isolated limb perfusion (HILP) should be considered in affected patients. In the present study, we have analyzed the results of HILPs performed in our...See full text at original site
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引用元：
https://doi.org/10.1016/j.suronc.2021.101603

データ提供：米国国立医学図書館（NLM）

Isolated Limb Perfusion for Metastasized Malignant Melanoma

This research delves into the complex realm of cancer treatment, exploring the efficacy of hyperthermic isolated limb perfusion (HILP) in managing locoregional metastases of malignant melanoma. The researchers embarked on a retrospective analysis of HILP procedures performed in their department, seeking to evaluate the effectiveness of this technique in combating this aggressive form of cancer. Their findings highlight the potential of HILP as a valuable therapeutic option for selected patients with locoregional melanoma metastases.

Effective Treatment Option for Locoregional Melanoma Metastases

The study reported high remission rates (90%) following HILP, with both partial and complete responses observed. This discovery is like finding a hidden oasis in the vast desert of cancer research, offering a potential avenue for effective treatment for those with locoregional melanoma metastases. However, the study also acknowledged the potential for side effects and adverse events associated with HILP.

A Targeted Approach to Treating Melanoma

This research underscores the importance of a targeted approach to treating melanoma, highlighting the potential benefits of HILP for selected patients. It's like using a precise compass to navigate the intricate terrain of cancer treatment. The study suggests that HILP may be a valuable therapeutic option for patients with locoregional melanoma metastases, but careful patient selection and management of potential side effects are crucial.

Dr. Camel's Conclusion

This research sheds light on the potential of hyperthermic isolated limb perfusion (HILP) as a treatment option for patients with locoregional melanoma metastases. It's like discovering a hidden oasis in the vast desert of cancer research, offering a potential avenue for effective treatment for those with this aggressive form of cancer. While HILP carries potential risks, the study suggests that it may be a valuable tool for carefully selected patients.

Date :
  1. Date Completed 2022-01-17
  2. Date Revised 2022-01-17
Further Info :

Pubmed ID

33992896

DOI: Digital Object Identifier

10.1016/j.suronc.2021.101603

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Languages

English

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