Safety review of tenofovir disoproxil fumarate/emtricitabine pre-exposure prophylaxis for pregnant women at risk of HIV infection.

Author: MugwanyaKenneth K, PintyeJillian, StalterRandy M

Paper Details 
Original Abstract of the Article :
<b>Introduction</b>: Pregnancy is a period of elevated HIV risk in high-burden settings, motivating the need for prevention tools that are both safe for use and effective during pregnancy. Oral pre-exposure prophylaxis (PrEP) containing tenofovir disoproxil fumarate (TDF) is recommended by the Worl...See full text at original site
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引用元:
https://pubmed.ncbi.nlm.nih.gov/33998936

データ提供:米国国立医学図書館(NLM)

The Safety of Tenofovir Disoproxil Fumarate/Emtricitabine Pre-Exposure Prophylaxis for Pregnant Women

This research tackles a crucial challenge in the field of HIV prevention: finding safe and effective tools for pregnant women in high-risk settings. The study delves into the safety of Tenofovir Disoproxil Fumarate (TDF)-based pre-exposure prophylaxis (PrEP) during pregnancy. It leverages a comprehensive approach, combining clinical pharmacology, efficacy data, and safety evidence from relevant studies. The authors carefully assess the potential impact of TDF-based PrEP on both maternal and infant health.

TDF/FTC PrEP: A Safe Option for Pregnant Women

The research indicates that TDF/FTC PrEP is not linked to an increased risk of adverse pregnancy outcomes or early infant growth problems. This is a very promising finding, as it suggests that PrEP can be a valuable tool for protecting pregnant women against HIV infection without posing additional health risks to either mother or baby.

Balancing Safety and Effectiveness: A Camel's Perspective

As a camel, I've seen my share of challenging journeys across the desert. Just like a camel navigates a challenging landscape, this research aims to find the safest and most effective path to protect pregnant women from the harsh reality of HIV infection. This research highlights the importance of continuous monitoring and data collection to ensure that PrEP remains a safe and effective option for pregnant women. It's like ensuring a steady supply of water in the desert - a critical element for successful navigation.

Dr.Camel's Conclusion

The study suggests that TDF/FTC PrEP is a safe and effective option for protecting pregnant women against HIV infection. However, ongoing research is crucial to ensure the long-term safety and efficacy of this preventative measure. Just as a camel needs to constantly adapt to the changing desert environment, so too must we adapt our understanding of PrEP's impact on both mothers and their children.

Date :
  1. Date Completed 2021-11-03
  2. Date Revised 2022-11-19
Further Info :

Pubmed ID

33998936

DOI: Digital Object Identifier

NIHMS1782965

Related Literature

SNS
PICO Info
in preparation
Languages

English

Positive IndicatorAn AI analysis index that serves as a benchmark for how positive the results of the study are. Note that it is a benchmark and requires careful interpretation and consideration of different perspectives.

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