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Management of Opioid-Induced Constipation and Bowel Dysfunction: Expert Opinion of an Italian Multidisciplinary Panel.

Author: CaraceniAugusto, ChiarioniGiuseppe, CorazziariEnrico Stefano, De GiorgioRoberto, GiustiRaffaele, MarinangeliFranco, MercadanteSebastiano, OdettiPatrizio, PintoCarmine, ZuccoFurio Massimino

Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.
Research Support, Non-U.S. Gov'tResearch funding provided by government agencies outside the United States.
ReviewAn article that critically examines existing research on a particular topic and summarizes the current state of knowledge in the field.

Overview

Managing opioid-induced constipation (OIC) involves preventative measures and pharmacological treatment, with laxatives as first-line therapy and peripherally acting μ opioid receptor antagonists as second-line options.
Paper Details　
Original Abstract of the Article :
The prescribing and use of opioid analgesics is increasing in Italy owing to a profusion in the number and types of opioid analgesic products available, and the increasing prevalence of conditions associated with severe pain, the latter being related to population aging. Herein we provide the expert...See full text at original site
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引用元：
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8279968/

データ提供：米国国立医学図書館（NLM）

Management of Opioid-Induced Constipation and Bowel Dysfunction: An Expert Opinion

The use of opioid analgesics is increasing, leading to a greater awareness of their potential side effects, particularly opioid-induced constipation (OIC). This research presents the expert opinion of an Italian multidisciplinary panel on the management of OIC and opioid-induced bowel dysfunction. The authors review the various pharmacological and non-pharmacological approaches to managing OIC, providing guidance for healthcare providers and patients.

Addressing Opioid-Induced Constipation: A Multifaceted Approach

The study highlights the importance of a multidisciplinary approach to managing OIC, encompassing lifestyle modifications, pharmacological interventions, and personalized treatment plans. The authors provide a comprehensive overview of treatment options, ranging from first-line laxatives to second-line peripherally acting μ-opioid receptor antagonists (PAMORAs).

Navigating the Desert of Constipation: A Journey Towards Relief

As Dr. Camel, I understand the discomfort and frustration associated with constipation, especially when it's a side effect of necessary medication. This research provides valuable insights into the management of OIC, reminding us that relief is often achievable through a combination of strategies.

Dr. Camel's Conclusion

This expert opinion provides valuable insights into the management of opioid-induced constipation and bowel dysfunction. It highlights the importance of a multidisciplinary approach, encompassing lifestyle modifications, pharmacological interventions, and personalized treatment plans to effectively manage this common side effect of opioid analgesics.

Date :
  1. Date Completed 2021-08-05
  2. Date Revised 2022-02-18
Further Info :

Pubmed ID

34086265

DOI: Digital Object Identifier

PMC8279968

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Languages

English

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