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Frequently Reported Adverse Events With Smoking Cessation Medications: Post Hoc Analysis of a Randomized Trial.

Author: DutroMichael P, EbbertJon, FisherMatt, HaysJ Taylor, Jimenez-RuizCarlos, LiJing

Multicenter StudyResearch conducted in collaboration with multiple research institutions. It aims to collect a wide range of data and obtain more generalizable results.
Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.
Randomized Controlled TrialA clinical trial that randomly assigns participants to treatment and control groups to evaluate the effects of an intervention.
Research Support, Non-U.S. Gov'tResearch funding provided by government agencies outside the United States.

Overview

Varenicline, bupropion, and nicotine patch were well-tolerated for smoking cessation. The most common adverse events were nausea, insomnia, abnormal dreams, anxiety, irritability, dry mouth, fatigue, and application site pruritus.
Paper Details　
Original Abstract of the Article :
OBJECTIVE: To compare the incidence, severity, and clinical course of frequently reported adverse events (AEs) after treatment with smoking cessation pharmacotherapies. METHODS: This was a multinational, multicenter, post hoc analysis of frequently reported treatment-emergent AEs from a large, phas...See full text at original site
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引用元：
https://doi.org/10.1016/j.mayocp.2020.10.046

データ提供：米国国立医学図書館（NLM）

Navigating the Side Effects of Smoking Cessation Medications

Dr. Camel here, ready to embark on a journey through the world of smoking cessation medications. This study focuses on the adverse events associated with three commonly prescribed medications: varenicline, bupropion, and nicotine patch. Think of these medications as different desert trails, each offering a path to freedom from the grip of nicotine addiction. This study compares the potential side effects of each trail, helping smokers make informed decisions about their journey to a smoke-free life.

Side Effects: A Common Challenge on the Path to Quitting

The researchers found that all three medications were generally well-tolerated, but some side effects were more common than others. Nausea was the most frequent side effect associated with varenicline, while insomnia and abnormal dreams were more common with bupropion. The nicotine patch was generally associated with fewer side effects, primarily application site reactions. It's like encountering minor obstacles on the desert trails, but these are usually manageable and don't deter most travelers from reaching their goal.

Choosing the Right Trail for a Smoke-Free Life

This study provides valuable information for smokers considering medication to aid their quit attempt. The findings highlight the importance of consulting with a healthcare professional to discuss individual risks and benefits of each medication. It's like choosing the best desert trail, considering the terrain, weather conditions, and your own capabilities. Remember, there is no one-size-fits-all approach to quitting smoking. With the right guidance and support, you can find the path that leads to a smoke-free life.

Dr. Camel's Conclusion

This research provides valuable insights into the side effect profiles of smoking cessation medications, highlighting the importance of individualized treatment approaches. It's like offering a comprehensive guide to the desert trails of smoking cessation, helping smokers navigate the challenges and reach their destination. This journey of discovery continues, seeking to provide smokers with the best possible tools and support to conquer their addiction and achieve a smoke-free life.

Date :
  1. Date Completed 2021-07-22
  2. Date Revised 2021-09-22
Further Info :

Pubmed ID

34112520

DOI: Digital Object Identifier

10.1016/j.mayocp.2020.10.046

Related Literature

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・Side Effects of varenicline
SNS
PICO Info
in preparation
Languages

English

Positive IndicatorAn AI analysis index that serves as a benchmark for how positive the results of the study are. Note that it is a benchmark and requires careful interpretation and consideration of different perspectives.

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