[Elucidation of Influential Factors on Nausea Associated with Olaparib Administration].

Author: HaradaDai, KageyamaAkira, KawakuboTakashi, NagasakiEijiro, NakagomiSanae, NakazawaYusuke, SuzukiJiro

Paper Details 
Original Abstract of the Article :
Olaparib, an anticancer drug, requires daily administration, frequently causing nausea. Elucidation of the influential factors for nausea is important for continuing treatment. We retrospectively examined 23 patients who received olaparib treatment and were divided into nausea and no-nausea groups, ...See full text at original site
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引用元:
https://pubmed.ncbi.nlm.nih.gov/34139728

データ提供:米国国立医学図書館(NLM)

Olaparib: Navigating the Side Effects of a Promising Anticancer Drug

Olaparib, an anticancer drug that offers hope for patients battling various cancers, can sometimes come with side effects. This study, much like a caravan venturing into uncharted territory, examines the factors that contribute to nausea, a common side effect of olaparib. The researchers retrospectively analyzed data from 23 patients who received olaparib treatment, comparing those who experienced nausea to those who did not. They explored potential correlations between patient characteristics and the occurrence of nausea.

Body Weight: A Potential Factor in Olaparib-Induced Nausea

The study found a significant association between lower body weight and the development of nausea in patients receiving olaparib treatment. This finding suggests that underweight individuals may be more prone to experiencing this side effect. The study also found that patients with lower body weight had a longer treatment duration, hinting at potential challenges in managing olaparib therapy in underweight patients.

Navigating the Desert of Anticancer Treatment

This research provides valuable insights into the potential role of body weight in the development of olaparib-induced nausea. This finding could help healthcare providers identify patients at higher risk and implement strategies to mitigate this side effect. Further research is needed to fully understand the relationship between body weight and olaparib-induced nausea, but this study offers a roadmap for navigating this challenging aspect of cancer treatment. We can learn from this desert journey and strive to provide patients with the best possible care, minimizing side effects and maximizing the benefits of innovative treatments.

Dr. Camel's Conclusion

This research offers a valuable perspective on the side effects of olaparib, highlighting the potential role of body weight in the development of nausea. The findings emphasize the importance of considering individual patient characteristics when managing olaparib therapy, potentially leading to improved treatment outcomes. As we continue to explore the complexities of cancer treatment, this research reminds us that even seemingly simple factors like body weight can significantly impact the patient experience.

Date :
  1. Date Completed 2021-06-21
  2. Date Revised 2021-06-21
Further Info :

Pubmed ID

34139728

DOI: Digital Object Identifier

34139728

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SNS
PICO Info
in preparation
Languages

Japanese

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