Features and Outcomes of Microcrystalline Arthritis Treated by Biologics: A Retrospective Study.

Author: BouvardBéatrice, CoiffierGuillaume, DernisEmmanuelle, DoaréElise, GervaisElisabeth, GoupillePhilippe, GuggenbuhlPascal, Le MélédoGuillaume, MarhadourThierry, OrioneCharles, RacapéHélène, RobinFrançois, SarauxAlain

Paper Details 
Original Abstract of the Article :
OBJECTIVES: The usual treatments for crystal-associated arthritis are sometimes contraindicated; thus, new therapies against interleukin-1beta (IL-1) have been developed. We evaluated the characteristics of patients who received biological treatment for crystal-associated arthritis. PATIENTS AND ME...See full text at original site
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引用元:
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8380607/

データ提供:米国国立医学図書館(NLM)

Exploring Biologic Treatment for Microcrystalline Arthritis

Microcrystalline arthritis, a condition characterized by the deposition of crystals in the joints, can cause debilitating pain and inflammation. This retrospective study investigates the characteristics and outcomes of patients treated with biologic therapies, primarily anakinra, for microcrystalline arthritis, specifically gouty arthritis and calcium pyrophosphate crystal deposition disease (CCPD). The researchers found that anakinra was prescribed for patients with refractory microcrystalline arthritis or contraindications to conventional treatments. The first course of biotherapy was more effective in treating gout than CCPD. Furthermore, urate-lowering therapy was more frequently used after the first biotherapy course for gout. This study provides valuable insights into the use of biologic therapies for microcrystalline arthritis, highlighting their potential benefits in managing refractory cases and the need for further investigation into their efficacy in treating different types of microcrystalline arthritis.

Biologic Therapies for Microcrystalline Arthritis: Navigating a New Frontier

This study sheds light on the emerging role of biologic therapies in treating microcrystalline arthritis. The findings suggest that anakinra may be a valuable therapeutic option for patients with refractory cases or contraindications to conventional treatments. The study's findings also highlight the need for further investigation into the optimal use of biologics in treating different types of microcrystalline arthritis, including CCPD. These insights are crucial for developing more effective and personalized treatment strategies for patients with this challenging condition.

The Desert of Microcrystalline Arthritis: Seeking Relief with Biologics

As a camel traversing the vast and unforgiving desert, I've learned that encountering a painful injury can be debilitating. Similarly, patients with microcrystalline arthritis experience significant pain and inflammation, often seeking relief from conventional treatments. This study provides valuable insights into the use of biologic therapies, such as anakinra, as potential alternatives or additions to conventional treatments, offering hope for patients seeking lasting relief from the debilitating effects of this condition.

Dr. Camel's Conclusion

This retrospective study explores the characteristics and outcomes of patients treated with biologic therapies, primarily anakinra, for microcrystalline arthritis. The findings suggest that anakinra may be a valuable therapeutic option for patients with refractory cases or contraindications to conventional treatments. The study also highlights the need for further investigation into the optimal use of biologics in treating different types of microcrystalline arthritis.
Date :
  1. Date Completed n.d.
  2. Date Revised 2021-11-10
Further Info :

Pubmed ID

34218418

DOI: Digital Object Identifier

PMC8380607

Related Literature

SNS
PICO Info
in preparation
Languages

English

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