Paper Details 
Original Abstract of the Article :
Histamine in the brain is produced by a group of tuberomamillary neurons in the posterior hypothalamus and a limited number of mast cells in different parts of the brain. Four G-protein-coupled receptors mediate the effects of histamine. Two of these receptors, H3 and H4 receptors, are high-affinity...See full text at original site
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引用元:
https://doi.org/10.1016/B978-0-12-820107-7.00023-9

データ提供:米国国立医学図書館(NLM)

Histamine: A Versatile Messenger in Health and Disease

The role of [histamine] in the brain and immune system is a complex and fascinating area of research. This article provides a comprehensive overview of histamine receptors, their agonists, and antagonists, highlighting their implications in both health and disease. The authors explore the diverse functions of histamine in the brain, including its role in alertness and wakefulness, as well as its involvement in various immune responses. The article also delves into the potential therapeutic applications of histamine receptor ligands in treating conditions like narcolepsy, hypersomnia, allergy, and gastric ulcers.

Histamine Receptors: A Complex Network of Signaling

This research delves into the intricate world of histamine receptors, their ligands, and their implications in health and disease. It highlights the multifaceted role of histamine in the brain and immune system. Much like the intricate network of dunes in the desert, histamine receptors act as signaling hubs, mediating diverse physiological processes. This comprehensive analysis provides valuable insights into the potential of histamine receptor ligands in treating various conditions.

Unlocking the Potential of Histamine Receptor Ligands

The study sheds light on the diverse therapeutic potential of histamine receptor ligands in treating conditions like narcolepsy, hypersomnia, allergy, and gastric ulcers. This research, like a camel traversing the vast desert, opens new pathways for developing effective treatments by targeting specific histamine receptors. Further research is needed to fully understand the therapeutic potential of these ligands and ensure their safe and effective application in clinical settings.

Dr.Camel's Conclusion

Histamine, like the shifting sands of the desert, plays a dynamic role in our bodies. This research offers valuable insights into the complexities of histamine signaling, highlighting its importance in both health and disease. By understanding these intricacies, we can pave the way for new and effective treatments, just as a camel navigating the desert relies on its innate knowledge to find its way. This study underscores the importance of continued research in this fascinating field.

Date :
  1. Date Completed 2021-07-28
  2. Date Revised 2021-07-28
Further Info :

Pubmed ID

34225942

DOI: Digital Object Identifier

10.1016/B978-0-12-820107-7.00023-9

Related Literature

SNS
PICO Info
in preparation
Languages

English

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