Anti-growth and pro-apoptotic effects of dasatinib on human oral cancer cells through multi-targeted mechanisms.

Author: Bishop-BaileyDavid, ChoiJong-Soon, JangByeong-Churl, ParkJong Wook, ParkNam-Sook, ParkYu-Kyung, ShinYoung-Min, YadavAnil Kumar

Paper Details 
Original Abstract of the Article :
Dasatinib is an inhibitor of Src that has anti-tumour effects on many haematological and solid cancers. However, the anti-tumour effects of dasatinib on human oral cancers remain unclear. In this study, we investigated the effects of dasatinib on different types of human oral cancer cells: the non-t...See full text at original site
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引用元:
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8419177/

データ提供:米国国立医学図書館(NLM)

Dasatinib: A New Weapon in the Fight Against Oral Cancer

The battle against cancer, like a desert war, demands a constant search for new and effective weapons. This study, like a skilled warrior exploring a new battlefield, investigates the anti-tumor effects of dasatinib, a potent drug, on human oral cancer cells. The researchers, driven by the desire to improve treatment outcomes, conducted a series of experiments examining the impact of dasatinib on different types of oral cancer cells. Their findings, like a successful military campaign, reveal that dasatinib effectively suppressed the growth of oral cancer cells and induced apoptosis, offering a promising new treatment option for this challenging disease. The study also delves into the mechanisms of action, revealing that dasatinib targets multiple signaling pathways, including Src, EGFR, STAT-3, and ERK-1/2, further solidifying its potential as a potent anti-cancer agent.

A Multi-Pronged Attack

The study demonstrates the effectiveness of dasatinib in combating oral cancer, highlighting its ability to target multiple pathways involved in cancer growth and survival. This multi-pronged approach, like a coordinated military offensive, increases the likelihood of success in treating this challenging disease.

Navigating the Desert of Cancer Treatment

Oral cancer, like a formidable desert enemy, poses significant challenges to healthcare professionals and patients. This study, like a strategic guidebook for navigating this battlefield, provides valuable insights into the potential of dasatinib to effectively combat this disease, offering hope and optimism for the future of oral cancer treatment.

Dr.Camel's Conclusion

This research is like a desert warrior discovering a powerful new weapon - dasatinib offers a promising new approach to combatting oral cancer. Its ability to target multiple signaling pathways and induce apoptosis, like a well-executed military strategy, underscores its potential as a valuable tool in the fight against this challenging disease. This research is a testament to the ongoing pursuit of new and effective therapies, reminding us that even in the face of formidable challenges, there is always hope for a brighter future.

Date :
  1. Date Completed 2022-02-14
  2. Date Revised 2023-11-07
Further Info :

Pubmed ID

34318593

DOI: Digital Object Identifier

PMC8419177

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Languages

English

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