Efficacy of erlotinib and its effects on the quality of life of older patients with epidermal growth factor receptor-mutant non-small cell lung cancer: A prospective, multicenter, dose-modification study.

Author: FujitakaKazunori, HamaguchiMegumi, HamaguchiShunichi, HamaiKosuke, HottaTakamasa, IshikawaNobuhisa, IsobeTakeshi, MasudaTakeshi, SutaniAkihisa, TaninoAkari, TaniwakiMasaya, TsubataYukari, YamasakiMasahiro

Paper Details 
Original Abstract of the Article :
Gefitinib and erlotinib are efficacious and safe for older patients with epidermal growth factor receptor-mutant non-small cell lung cancer. However, prolonged use of epidermal growth factor receptor-tyrosine kinase inhibitors in older patients is difficult, owing to potential adverse events. Hence,...See full text at original site
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引用元:
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8518893/

データ提供:米国国立医学図書館(NLM)

Erlotinib: A Tailored Approach for Older Patients with Lung Cancer

Epidermal growth factor receptor (EGFR)-mutant non-small cell lung cancer (NSCLC) is a challenging disease, particularly for older patients. This study, like a camel navigating a treacherous mountain pass, explores the efficacy and safety of low-dose erlotinib in treating older patients with EGFR-mutant NSCLC. The researchers, using a [prospective, multicenter, dose-modification study], carefully monitored the effects of erlotinib on tumor response and quality of life. Their findings highlight the potential of individualized dose adjustments to maximize therapeutic benefit while minimizing potential adverse events in older patients with lung cancer.

A Personalized Approach: Tailoring Treatment for Older Patients

This study underscores the importance of personalized medicine in treating older patients with lung cancer. By carefully adjusting the dose of erlotinib, the researchers were able to achieve therapeutic efficacy while minimizing potential side effects. This approach, like a camel caravan adapting its route based on the terrain, allows for a more effective and personalized treatment strategy for older patients.

Living Well with Lung Cancer: The Role of Personalized Treatment

The study's findings highlight the importance of individualized care in treating older patients with lung cancer. By carefully adjusting the dose of erlotinib, healthcare professionals can work collaboratively with patients to optimize treatment outcomes and improve overall quality of life. This personalized approach, like a camel's ability to adapt to the harsh desert environment, can help patients navigate the challenges of lung cancer and maintain a sense of well-being.

Dr.Camel's Conclusion

This study, like a wise camel navigating a complex desert landscape, demonstrates the value of a personalized approach to treating older patients with EGFR-mutant non-small cell lung cancer. By adjusting erlotinib dosage, healthcare providers can maximize therapeutic benefit while minimizing potential side effects, improving overall quality of life for these patients.

Date :
  1. Date Completed 2021-10-05
  2. Date Revised 2022-05-31
Further Info :

Pubmed ID

34378299

DOI: Digital Object Identifier

PMC8518893

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English

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