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Drugs Associated With Ischemic Stroke: A Review for Clinicians.

Author: LivioFrancoise, MartoJoão Pedro, MichelPatrik, StramboDavide

Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.
ReviewAn article that critically examines existing research on a particular topic and summarizes the current state of knowledge in the field.

Overview

This review assessed the association between frequently used drugs and ischemic stroke (IS) risk. A high level of association was found for erythropoietin, combined contraceptives, oral estrogen replacement therapy, bevacizumab, tamoxifen, and antipsychotics. A moderate level of association was identified for ponatinib, nilotinib, darunavir, and gonadotropin-releasing hormone agonists. For many drugs, no association was found, and for others, insufficient data prevented categorization.
Paper Details　
Original Abstract of the Article :
Certain drugs may increase the risk of ischemic stroke (IS). Our goal was to review associations between frequently used drugs and IS. We created an initial list of frequently used drugs to search Pubmed/MEDLINE from 1966 to 2020 and reviewed phase III and IV data, case series, and drug authorities'...See full text at original site
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引用元：
https://doi.org/10.1161/STROKEAHA.120.033272

データ提供：米国国立医学図書館（NLM）

Drugs and Stroke: A Comprehensive Review of Potential Risks

Ischemic stroke, a serious cerebrovascular event, can have devastating consequences. This comprehensive review examines the potential association between commonly used drugs and the risk of ischemic stroke. The authors provide a valuable resource for clinicians, summarizing the available evidence regarding the association between various drug classes and ischemic stroke risk.

Navigating Drug Safety: A Guide to Potential Stroke Risks

This review identifies a high level of association between ischemic stroke and several frequently used drugs, including erythropoietin, combined contraceptives, oral estrogen replacement therapy, bevacizumab, tamoxifen, and antipsychotics. The authors also highlight a moderate level of association for ponatinib, nilotinib, darunavir, and gonadotropin-releasing hormone agonists. This information is crucial for clinicians to consider when prescribing these drugs, carefully evaluating the potential risks and benefits for each patient.

Understanding Drug-Induced Risks: Protecting Patients and Promoting Safety

This review serves as a valuable resource for healthcare professionals, providing a comprehensive overview of the potential associations between commonly used drugs and the risk of ischemic stroke. By understanding these potential risks, clinicians can make informed decisions about prescribing medications, balancing the potential benefits with the potential risks for each individual patient.

Dr.Camel's Conclusion

This study, like a carefully crafted map guiding travelers through a vast and potentially treacherous desert, provides clinicians with valuable insights into the potential risks associated with commonly prescribed medications. By understanding these potential risks, clinicians can make informed decisions about drug selection and dosage, promoting patient safety and optimizing treatment outcomes.

Date :
  1. Date Completed 2022-01-07
  2. Date Revised 2022-01-07
Further Info :

Pubmed ID

34404236

DOI: Digital Object Identifier

10.1161/STROKEAHA.120.033272

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Languages

English

Positive IndicatorAn AI analysis index that serves as a benchmark for how positive the results of the study are. Note that it is a benchmark and requires careful interpretation and consideration of different perspectives.

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