Clinical experience with titrating doses of digoxin antibodies in acute digoxin poisoning. (ATOM-6).

Author: BuckleyNicholas A, ChanBetty S, ChiewAngela, IsbisterGeoffrey K, IsoardiKatherine

Paper Details 
Original Abstract of the Article :
For acute digoxin poisoning, it has been recommended to give bolus doses of 10-20 vials or potentially larger than needed doses calculated from dose ingested or the measured concentration. However, a recent revision of internal Poisons Information Centre guidelines prompted a change of our recommend...See full text at original site
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引用元:
https://doi.org/10.1080/15563650.2021.1968422

データ提供:米国国立医学図書館(NLM)

Titrating Digoxin Antibodies: A Precise Approach to Digoxin Poisoning

Digoxin poisoning is a serious medical emergency requiring prompt and effective treatment. This study examined the clinical experience of using titrating doses of digoxin antibodies (Digoxin-Fab) in managing acute digoxin poisoning. The researchers, like skilled desert healers, sought to optimize the use of Digoxin-Fab to effectively counteract the harmful effects of digoxin toxicity.

Titrating Digoxin Antibodies: A More Targeted Approach

The study advocated for the use of repeated low doses of Digoxin-Fab, titrated based on bedside assessment of cardiac toxicity, rather than administering large bolus doses. This approach, like a desert physician carefully adjusting a patient's medication based on their individual needs, allows for a more precise and personalized response to digoxin poisoning. The researchers found that this approach was effective in managing digoxin toxicity and reducing the need for large bolus doses.

Understanding the Importance of Tailored Treatment

This study highlights the importance of personalized treatment approaches in managing complex medical conditions like digoxin poisoning. It underscores the need for ongoing assessment and adjustments based on individual patient responses to optimize treatment outcomes. This research, like a guidebook for navigating the desert of digoxin toxicity, provides valuable insights for healthcare professionals.

Dr. Camel's Conclusion

This study, like a well-placed oasis offering a source of healing, emphasizes the importance of a tailored approach to managing digoxin poisoning. It's a testament to the ongoing evolution of medical practice, driven by a commitment to providing the most effective and safe care for patients.

Date :
  1. Date Completed 2022-03-31
  2. Date Revised 2022-04-26
Further Info :

Pubmed ID

34424803

DOI: Digital Object Identifier

10.1080/15563650.2021.1968422

Related Literature

SNS
PICO Info
in preparation
Languages

English

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