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Antibiotic prophylaxis in orthognathic surgery: an overview of systematic reviews.

Author: FavoretoA X P, GilA P S, HaasO L, Machado-FernándezA, Muñoz-PereiraM E, VelasquesB D, da RosaB M, de OliveiraR B

Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.
ReviewAn article that critically examines existing research on a particular topic and summarizes the current state of knowledge in the field.

Overview

Long-term antibiotic therapy reduces the risk of surgical site infection in orthognathic surgery, but the optimal regimen and duration remain uncertain.
Paper Details　
Original Abstract of the Article :
The purpose of this overview was to assess different antibiotic regimens used in orthognathic surgery and to establish an evidence-based protocol so that beneficial and adverse effects can be determined. A comprehensive literature search for systematic reviews and/or meta-analyses was conducted in M...See full text at original site
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引用元：
https://doi.org/10.1016/j.bjoms.2021.05.010

データ提供：米国国立医学図書館（NLM）

A Journey Through Antibiotic Prophylaxis in Orthognathic Surgery: Seeking the Best Path to Prevent Infections

This overview of systematic reviews assesses the effectiveness of different antibiotic regimens used in orthognathic surgery, aiming to establish evidence-based protocols to minimize the risk of surgical site infections (SSIs). It's like navigating a vast desert landscape, seeking the most effective strategies to avoid the dangers that lie ahead.

Seeking the Oasis of Infection Prevention: Exploring Antibiotic Regimens

The overview reveals that long-term antibiotic therapies, such as penicillin, cefazolin-cephalexin, and amoxicillin-clavulanic acid, are associated with lower infection rates, ranging from 0% to 3.13%. In contrast, placebo groups and short-term penicillin therapy reported higher rates of SSIs (52.6% and 60%, respectively). This suggests that prolonged antibiotic prophylaxis may offer a more robust protection against infections.

Navigating the Terrain of Side Effects: A Balance of Benefits and Risks

The overview also highlights the potential side effects associated with certain antibiotics, including nausea, pain, swelling, headache, vomiting, and skin rash. This emphasizes the importance of carefully considering the balance between benefits and risks when selecting antibiotic regimens for orthognathic surgery. It's like choosing a path through a desert where the terrain may be challenging, but the benefits of reaching the oasis outweigh the risks.

Dr.Camel's Conclusion

This overview highlights the importance of evidence-based decision-making when choosing antibiotic regimens for orthognathic surgery, striking a balance between minimizing infection risk and managing potential side effects. It's like navigating a vast desert landscape, where choosing the right path requires careful consideration of the terrain, potential obstacles, and the ultimate destination. By understanding the evidence and weighing the risks and benefits, surgeons can best protect their patients from the dangers of SSIs while ensuring their overall well-being.
Date :
  1. Date Completed 2022-08-30
  2. Date Revised 2022-09-01
Further Info :

Pubmed ID

34465488

DOI: Digital Object Identifier

10.1016/j.bjoms.2021.05.010

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Languages

English

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