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Inhibition of Aspirin-Induced Gastrointestinal Injury: Systematic Review and Network Meta-Analysis.
Author: HuaGuo-Dong, LangRui, LiQiu-Yan, WangMiao-Ran, WangXu-Jie, WengWei-Liang, XueChun-Miao, ZhangWan-Tong, ZhuBao-Chen
Original Abstract of the Article :
<b>Background:</b> Administration of aspirin has the potential for significant side effects of gastrointestinal (GI) injury mainly caused by gastric acid stimulation, especially in long-term users or users with original gastrointestinal diseases. The debate on the optimal treatment of aspirin-induc...See full text at original site
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引用元:
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8406693/
データ提供:米国国立医学図書館(NLM)
Exploring Treatment Options for Aspirin-Induced Gastrointestinal Injury
Aspirin, a widely used medication with numerous therapeutic benefits, can sometimes cause unwanted gastrointestinal side effects, particularly in long-term users or those with pre-existing digestive conditions. This study aims to compare and rank different treatments for aspirin-induced gastrointestinal injury, relying on current evidence from randomized controlled trials (RCTs).
Omeprazole Plus Rebamipide: A Potential Leader in Gastrointestinal Protection
This systematic review and network meta-analysis included data from 10 RCTs involving 503 participants. The researchers evaluated the effectiveness of various treatments, including omeprazole, lansoprazole, famotidine, misoprostol, and others. Their analysis suggested that omeprazole plus rebamipide might be the most effective treatment for preventing aspirin-induced gastrointestinal injury. While this study provides valuable insights, the authors acknowledge the need for further large-scale RCTs to confirm these findings.
Protecting Your Gut While Enjoying Aspirin's Benefits
This research highlights the importance of understanding the potential risks and benefits of medications, especially those that are widely used, like aspirin. For those who need to take aspirin long-term, consulting with their doctor about potential gastrointestinal side effects and exploring preventive measures is essential. Just as a camel seeks out the safest paths in the desert, individuals should be mindful of potential risks and take precautions to protect their health.
Dr.Camel's Conclusion
This systematic review provides a comprehensive overview of treatment options for aspirin-induced gastrointestinal injury. The findings suggest that omeprazole plus rebamipide may be a promising approach to minimizing these side effects. However, further research is crucial to solidify these conclusions and inform future clinical practice. This study underscores the importance of individualizing treatment plans and carefully considering potential risks and benefits when managing aspirin-related gastrointestinal issues.
Date :
- Date Completed n.d.
- Date Revised 2021-09-04
Further Info :
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