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Systematic Review and Recommendations to Combine Newer Therapies With Conventional Therapy in Psoriatic Disease.

Author: AroraGulhima, AroraSandeep, DasPankaj

Systematic ReviewA review that systematically collects, evaluates, and integrates relevant research to answer a specific research question.

Overview

Psoriasis is a chronic skin condition, and while new treatments have been developed, sometimes they don't work well enough on their own. This review examines research on combining newer and older treatments for psoriasis to improve results. The review found that combining specific medications, like acitretin and light therapy, or certain older medications with newer biologics, can improve effectiveness and reduce side effects. However, combining some medications, like cyclosporine and light therapy, is not recommended due to increased risk of skin cancer. This review aims to provide guidance on combining treatments for psoriasis based on the available evidence.
Paper Details　
Original Abstract of the Article :
<b>Background:</b> Psoriasis continues to have unmet needs in its management despite introduction of newer molecules. Monotherapy with these newer agents may not achieve therapeutic goals in all cases, hence necessitating their combinations with other molecules. Improved understanding of newer as w...See full text at original site
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引用元：
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8416676/

データ提供：米国国立医学図書館（NLM）

Combining Therapies for Psoriatic Disease: A Comprehensive Review

This systematic review explores the use of combination therapies for psoriatic disease, a chronic skin condition. Imagine psoriasis as a persistent desert sandstorm, causing inflammation and irritation. The researchers examine the effectiveness of combining different treatment strategies to combat this relentless storm.

The review highlights the potential benefits of combining newer therapies, such as biologic disease-modifying antirheumatic drugs (DMARDs) and apremilast, with conventional therapies, including methotrexate, cyclosporine, retinoids, and phototherapy. It emphasizes the need for a personalized approach to treatment based on individual patient needs and responses.

The Benefits of Combination Therapies

The review underscores the potential benefits of combination therapies in managing psoriatic disease. By combining different approaches, healthcare professionals can often achieve better outcomes and reduce the risk of side effects associated with individual therapies.

A Personalized Approach to Psoriasis Treatment

The review emphasizes the importance of a personalized approach to psoriatic disease treatment. Just as a desert traveler adapts their journey to the specific terrain, healthcare professionals need to tailor treatment plans to the individual needs of their patients.

Dr. Camel's Conclusion

This systematic review provides a comprehensive overview of the use of combination therapies for psoriatic disease. The research highlights the potential benefits of combining newer and conventional therapies to achieve optimal outcomes. Just as a desert nomad uses a variety of tools and strategies to navigate the challenging terrain, healthcare professionals must remain adaptable and innovative in their approach to managing this chronic condition.

Date :
  1. Date Completed n.d.
  2. Date Revised 2021-09-08
Further Info :

Pubmed ID

34490293

DOI: Digital Object Identifier

PMC8416676

Related Literature

Article Analysis
・Effective treatment of psoriasis
SNS
PICO Info
in preparation
Languages

English

Positive IndicatorAn AI analysis index that serves as a benchmark for how positive the results of the study are. Note that it is a benchmark and requires careful interpretation and consideration of different perspectives.

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