Late-onset hypophysitis after discontinuation of nivolumab treatment for advanced skin melanoma: a case report.

Author: AntoniouSofia, BazazoGeorgios, BergChristian, PapadakisMarios, RöcklLudwig

Paper Details 
Original Abstract of the Article :
Nivolumab is an anti-programmed cell death protein 1 antibody, typically used as cancer immunotherapy agent. Despite multiple clinical benefits it might cause autoimmune-related side-effects, often involving the endocrine system. To our knowledge, this is the first case of nivolumab-induced hypophys...See full text at original site
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引用元:
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8454065/

データ提供:米国国立医学図書館(NLM)

A Case of Late-Onset Hypophysitis: A Rare Side Effect of Nivolumab

Nivolumab, an immunotherapy drug used in cancer treatment, has revolutionized oncology. However, like a desert oasis that can also hide unexpected dangers, nivolumab can sometimes trigger autoimmune-related side effects. This case report describes a rare instance of late-onset hypophysitis, a condition affecting the pituitary gland, occurring several months after discontinuation of nivolumab treatment for advanced skin melanoma.

Navigating the Unknown: A Rare Side Effect

This case report highlights the importance of monitoring for potential side effects, even after discontinuation of immunotherapy drugs. It's like exploring a desert landscape - sometimes hidden dangers lurk beneath the surface. This case underscores the need for vigilance and careful follow-up care for patients receiving immunotherapy, ensuring early detection and management of potential complications.

A Reminder of Vigilance: The Importance of Monitoring

This report serves as a reminder that even innovative and life-saving treatments can have unexpected consequences. It's a reminder that the desert of medical knowledge is vast and full of surprises. This case emphasizes the importance of ongoing research to understand the full spectrum of side effects associated with immunotherapy drugs, ensuring the safety and well-being of patients.

Dr. Camel's Conclusion

While immunotherapy offers a beacon of hope for cancer patients, it's crucial to be aware of the potential for rare but serious side effects. This case report underscores the importance of careful monitoring and vigilant follow-up care for patients receiving immunotherapy, ensuring that they receive the best possible care and management of potential complications.

Date :
  1. Date Completed 2022-01-24
  2. Date Revised 2023-12-13
Further Info :

Pubmed ID

34544399

DOI: Digital Object Identifier

PMC8454065

Related Literature

SNS
PICO Info
in preparation
Languages

English

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