Treatment and Prevention of Periprosthetic Capsular Contracture in Breast Surgery With Prosthesis Using Leukotriene Receptor Antagonists: A Meta-Analysis.

Author: Achimaș-CadariuPatriciu Andrei, BonciEduard-Alexandru, ChiuzanCodruța, GâtaVlad Alexandru, JibocNicoleta Monica, MateiIleana Rodica, MunteanMaximilian Vlad, PașcaAndrei

Paper Details 
Original Abstract of the Article :
BACKGROUND: Capsular contracture (CC) is the most common long-term complication of breast surgery with prosthesis. Leukotriene receptor antagonists (LRAs) have been tested as a potential treatment; however, mixed results have been observed. OBJECTIVES: The aim of this study was to undertake a meta-...See full text at original site
Dr.Camel IconDr.Camel's Paper Summary Blogラクダ博士について

ラクダ博士は、Health Journal が論文の内容を分かりやすく解説するために作成した架空のキャラクターです。
難解な医学論文を、専門知識のない方にも理解しやすいように、噛み砕いて説明することを目指しています。

* ラクダ博士による解説は、あくまで論文の要点をまとめたものであり、原論文の完全な代替となるものではありません。詳細な内容については、必ず原論文をご参照ください。
* ラクダ博士は架空のキャラクターであり、実際の医学研究者や医療従事者とは一切関係がありません。
* 解説の内容は Health Journal が独自に解釈・作成したものであり、原論文の著者または出版社の見解を反映するものではありません。


引用元:
https://doi.org/10.1093/asj/sjab355

データ提供:米国国立医学図書館(NLM)

Leukotriene Receptor Antagonists: A Potential Solution for Capsular Contracture

Capsular contracture (CC) is a common complication following breast surgery with prosthesis. This research investigates the potential of leukotriene receptor antagonists (LRAs) in the management of CC, both as a treatment and as a prophylactic agent.

The study found that LRAs, particularly montelukast, can effectively manage CC when used as a treatment for ongoing cases. However, LRAs were not found to be effective as a prophylactic measure to prevent CC. This suggests that LRAs may be a valuable tool for managing existing CC but not for preventing its development.

Montelukast: A Promising Treatment for Capsular Contracture

The study's findings suggest that montelukast may be a valuable treatment option for patients with existing CC. This offers a potential solution for managing this common complication of breast surgery with prosthesis.

Navigating the Desert of Breast Surgery Complications: The Potential of LRAs

This research provides valuable insights into the potential of LRAs in managing CC. While not effective as a prophylactic agent, montelukast appears to be a promising treatment option for existing CC. This discovery could lead to improved management of this common complication, enhancing patient outcomes and quality of life.

Dr. Camel's Conclusion

This research, like a camel finding a hidden oasis in the vast desert of breast surgery complications, has revealed the potential of montelukast in managing capsular contracture. While not effective as a prophylactic measure, montelukast offers a promising treatment option for existing CC. This discovery could significantly improve the management of this common complication, offering relief and better outcomes for patients.

Date :
  1. Date Completed 2022-04-14
  2. Date Revised 2022-12-06
Further Info :

Pubmed ID

34618886

DOI: Digital Object Identifier

10.1093/asj/sjab355

Related Literature

SNS
PICO Info
in preparation
Languages

English

Positive IndicatorAn AI analysis index that serves as a benchmark for how positive the results of the study are. Note that it is a benchmark and requires careful interpretation and consideration of different perspectives.

This site uses cookies. Visit our privacy policy page or click the link in any footer for more information and to change your preferences.