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[Adrenal crisis associated with modafinil use].
Author: AquinosBrenda M, CanterosTeresa M, Fainstein-DayPatricia, García ArabehetyJulia, ScibonaPaula, de MiguelValeria
Original Abstract of the Article :
Adrenal crisis is the most extreme presentation form of adrenal insufficiency and represents a life-threatening endocrinological emergency. This situation can be triggered by different causes including the use of CYP3A4-inducing drugs, which accelerate hydrocortisone clearance. We describe the case ...See full text at original site
Dr.Camel's Paper Summary Blogラクダ博士について
ラクダ博士は、Health Journal が論文の内容を分かりやすく解説するために作成した架空のキャラクターです。
難解な医学論文を、専門知識のない方にも理解しやすいように、噛み砕いて説明することを目指しています。
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* ラクダ博士は架空のキャラクターであり、実際の医学研究者や医療従事者とは一切関係がありません。
* 解説の内容は Health Journal が独自に解釈・作成したものであり、原論文の著者または出版社の見解を反映するものではありません。
引用元:
https://pubmed.ncbi.nlm.nih.gov/34633961
データ提供:米国国立医学図書館(NLM)
Modafinil and Adrenal Crisis: A Case Study
This case study takes us on a journey through the delicate balance of [adrenal crisis] and the impact of certain medications. It's like a camel navigating a path through the scorching desert of hormonal imbalances, where even small changes can have significant consequences.
Modafinil: A Potential Trigger in the Desert of Adrenal Insufficiency
The study presents the case of an elderly woman with [secondary adrenal insufficiency] who experienced symptoms consistent with [adrenal crisis] after starting modafinil treatment. It's like a camel encountering a hidden hazard in the desert, a potential trigger for a dangerous reaction. The researchers suggest that modafinil may have precipitated the symptoms of adrenal insufficiency by [increasing the steroid clearance], like a sudden shift in the desert landscape.
Navigating the Desert of Adrenal Insufficiency: A Cautionary Tale
This case study serves as a stark reminder of the potential risks associated with certain medications, particularly for individuals with pre-existing conditions like adrenal insufficiency. It's like a camel navigating a treacherous terrain, where even a slight deviation from the path can lead to unexpected consequences. The study highlights the importance of careful monitoring and dose adjustment for patients taking medications that can affect the metabolism of corticosteroids.
Dr.Camel's Conclusion
This case study reveals the potential risks associated with the use of modafinil in individuals with adrenal insufficiency. The researchers underscore the importance of careful monitoring and dose adjustment for patients taking medications that can influence steroid metabolism. It's a valuable lesson for clinicians and patients alike, reminding us to tread carefully through the desert of medication interactions, where even seemingly harmless medications can have significant consequences. This case study is a reminder to always consult with a healthcare professional before starting any new medication and to stay vigilant about potential interactions and side effects.
Date :
- Date Completed 2021-10-13
- Date Revised 2021-10-13
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