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Sulfasalazine-induced drug reaction with eosinophilia and systemic symptoms (DRESS) with concomitant acute chikungunya virus infection: possible role of new viral trigger.

Author: BhattacharjeeMoni Sankar, ChandraAtanu, PramanikJayasri Das, SilAbheek

Case ReportsIn the medical field, a report that describes in detail a unique case, an unusual medical condition, or the effect of a treatment. Provides new insights and possibilities for treatment through individual patient cases.
Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.

Overview

This case report describes a patient with drug reaction with eosinophilia and systemic symptoms (DRESS) induced by sulfasalazine, a medication commonly used for inflammatory bowel disease. The patient also had coexisting chikungunya fever, making diagnosis challenging. The report highlights the rarity of sulfasalazine-induced DRESS and suggests that chikungunya virus could be a potential trigger for DRESS.
Paper Details　
Original Abstract of the Article :
Drug reaction with eosinophilia and systemic symptoms (DRESS) is designated as a potentially lethal adverse drug effect with characteristic signs and symptoms such as skin rash, fever, leucocytosis with eosinophilia or atypical lymphocytes, lymphadenopathy and liver or renal dysfunction. In addition...See full text at original site
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引用元：
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8513226/

データ提供：米国国立医学図書館（NLM）

Exploring the Intersection of Drug Reactions and Viral Infections

This research delves into the complex world of drug reactions, specifically drug reaction with eosinophilia and systemic symptoms (DRESS), a severe adverse drug effect. The study, a case report, describes a patient who experienced sulfasalazine-induced DRESS concurrently with acute chikungunya virus infection. The authors highlight the challenges in diagnosing DRESS when it coincides with other conditions, like a viral infection, and discuss the potential role of the virus as a triggering factor for DRESS.

A Complex Intersection of Drug Reactions and Viral Infections

The study reveals a significant finding – chikungunya virus could potentially trigger DRESS. This research underscores the importance of considering the interplay between drug reactions and viral infections in diagnosing and managing DRESS, offering a potential path to more accurate diagnosis and treatment.

Navigating the Complexities of Drug Reactions

This research emphasizes the importance of reporting any unusual or severe reactions to your doctor, especially if you are taking medication. Open communication with your healthcare provider can help ensure prompt diagnosis and appropriate treatment, minimizing the risks associated with potential drug reactions. Remember, like navigating a desert, understanding the potential hazards and communicating openly with your guide can help you avoid unforeseen obstacles.

Dr.Camel's Conclusion

This case report offers a valuable insight into the complex intersection of drug reactions and viral infections, highlighting the potential role of chikungunya virus as a triggering factor for DRESS. This research emphasizes the need for vigilance in diagnosing and managing DRESS, especially when it coincides with other conditions. This study serves as a reminder to healthcare professionals and patients alike to be mindful of the potential interplay between drug reactions and viral infections.

Date :
  1. Date Completed 2021-10-14
  2. Date Revised 2023-10-13
Further Info :

Pubmed ID

34642219

DOI: Digital Object Identifier

PMC8513226

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Languages

English

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