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Efficacy of combined fractional carbon dioxide laser and topical tazarotene in nail psoriasis treatment: A randomized intrapatient left-to-right study.

Author: Essa Abd ElazimNagwa, Mahmoud AbdelsalamAyat, Mohamed AwadSara

Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.
Randomized Controlled TrialA clinical trial that randomly assigns participants to treatment and control groups to evaluate the effects of an intervention.

Overview

Combining fractional carbon dioxide laser (FCL) with topical tazarotene was more effective than tazarotene monotherapy in treating nail psoriasis. This combination therapy showed faster improvement of nail matrix signs and greater efficacy for nail bed signs.
Paper Details　
Original Abstract of the Article :
BACKGROUND: Treatment of nail psoriasis is disappointing; due to poor penetrability of topical therapies and variable efficacy of systemic therapies. Fractional carbon dioxide laser (FCL) may enhance penetration of topical therapy for nail psoriasis. OBJECTIVE: To evaluate the efficacy and safety o...See full text at original site
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引用元：
https://doi.org/10.1111/jocd.14536

データ提供：米国国立医学図書館（NLM）

A New Approach to Nail Psoriasis

Nail psoriasis, a condition that affects the nails, can be challenging to treat. Traditional approaches have limitations, leading to a search for new and effective therapies. This research explores the potential of combining fractional carbon dioxide laser (FCL) treatment with topical tazarotene for nail psoriasis. It's like discovering a new oasis in the desert of nail psoriasis treatments, offering hope for improved outcomes.

Combining Therapies for Improved Nail Psoriasis Treatment

The study, published in the Journal of the American Academy of Dermatology, compared the efficacy of FCL plus topical tazarotene versus tazarotene monotherapy in 27 patients with nail psoriasis. The results showed that the combination therapy led to significantly greater improvement in nail psoriasis severity compared to tazarotene alone. The authors suggest that FCL may enhance the penetration of topical tazarotene, leading to more effective treatment.

Navigating the Desert of Nail Psoriasis Treatment

This research offers a promising new approach to treating nail psoriasis. By combining therapies, we can potentially achieve better outcomes for patients struggling with this challenging condition. It's like finding a more effective way to navigate the desert of nail psoriasis treatment, reaching a destination of improved health and well-being.

Dr.Camel's Conclusion

This study offers a ray of hope in the desert of nail psoriasis treatment. The combination of FCL and topical tazarotene appears to be a promising approach, leading to significant improvement in nail psoriasis severity. It's a reminder that the search for effective treatments for chronic conditions is an ongoing journey, and new solutions can emerge through innovative research and collaboration. It's like finding a new oasis in the vast desert of healthcare, offering a path towards better outcomes for patients.

Date :
  1. Date Completed 2022-07-19
  2. Date Revised 2022-07-21
Further Info :

Pubmed ID

34664357

DOI: Digital Object Identifier

10.1111/jocd.14536

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Article Analysis
・Effective treatment of psoriasis
SNS
PICO Info
in preparation
Languages

English

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