Kinetics of hydrocortisone sodium phosphate penetration into the human aqueous humor after topical application.

Author: AlabedHusam B R, CaginiCarlo, CastellucciGreta, LupidiMarco, MuziAlessio, PellegrinoRoberto Maria, RagnaGiulia

Paper Details 
Original Abstract of the Article :
Hydrocortisone is a soft steroid with low anti-inflammatory properties and a short duration of action, used to manage several ocular conditions. The clinical benefits and side effects associated with hydrocortisone are well documented, but its basic pharmacokinetic in the eye is yet to be fully eluc...See full text at original site
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引用元:
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9286650/

データ提供:米国国立医学図書館(NLM)

Hydrocortisone: A Soft Steroid's Journey to the Eye

The eye is a delicate organ, and understanding how medications penetrate its intricate structures is crucial for effective treatment. This study explores the penetration of hydrocortisone sodium phosphate into the human aqueous humor after topical application, providing insights into its pharmacokinetics. It's like observing a drop of water traversing the shifting sands of a desert, tracing its path and understanding its effects.

The study investigated the penetration capabilities of hydrocortisone when applied as eye drops at different concentrations. It aimed to understand how this soft steroid reaches the aqueous humor, the fluid that nourishes the eye.

Understanding Hydrocortisone's Journey

The study provides valuable information about the pharmacokinetic properties of hydrocortisone in the eye. This knowledge can help optimize treatment strategies, ensuring effective delivery of the drug to the desired location while minimizing potential side effects.

A Closer Look at Eye Care

The study highlights the importance of understanding the pharmacokinetics of medications used for eye care. By comprehending how drugs penetrate the eye's structures, we can develop more targeted and effective treatment approaches.

Dr.Camel's Conclusion

This study sheds light on the intricate journey of hydrocortisone through the eye, providing valuable insights into its pharmacokinetics. It reminds us that understanding the movement of medications within the body is crucial for ensuring effective treatment and minimizing potential side effects. Just as a camel navigates the desert with careful observation and understanding, we must approach eye care with a similar level of knowledge and precision.

Date :
  1. Date Completed 2021-12-31
  2. Date Revised 2022-07-31
Further Info :

Pubmed ID

34672064

DOI: Digital Object Identifier

PMC9286650

Related Literature

SNS
PICO Info
in preparation
Languages

English

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