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Case report: Stepwise transition from subcutaneous treprostinil to epoprostenol in high-risk pulmonary arterial hypertension.
Author: GagliardiJuan Alberto, MoriAna Laura, RodríguezAndrea, Stewart HarrisAlejandro
Original Abstract of the Article :
Idiopathic pulmonary arterial hypertension is associated with high morbidity and mortality. In recent years, the use of targeted therapies has led to an improvement in prognosis. Prostacyclin analogues treprostinil and epoprostenol require continuous subcutaneous or intravenous infusion and are gene...See full text at original site
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引用元:
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8530986/
データ提供:米国国立医学図書館(NLM)
Navigating the Transition from Treprostinil to Epoprostenol in Pulmonary Arterial Hypertension
Pulmonary arterial hypertension (PAH) is a serious condition that affects the blood vessels in the lungs, making it challenging for the heart to pump blood effectively. Prostacyclin analogues, such as treprostinil and epoprostenol, are crucial medications for PAH treatment. These medications require continuous infusion, either subcutaneously or intravenously. This study explores the complex process of transitioning patients from treprostinil to epoprostenol, particularly for high-risk individuals requiring higher doses of these medications, much like finding a safe and effective route through a challenging desert landscape.
A Stepwise Approach to Therapy
The researchers present a case report, detailing the successful transition of a high-risk PAH patient from treprostinil to epoprostenol. They emphasize the importance of a stepwise approach, gradually increasing the dose of epoprostenol while reducing the dose of treprostinil, ensuring patient safety and optimal therapeutic response. This careful transition helps minimize potential complications and achieve the desired therapeutic outcome.
Personalized Treatment for PAH
This case report highlights the importance of personalized treatment for PAH. Each patient's condition is unique, just as each desert landscape presents its own challenges. A healthcare professional's expertise is essential in determining the best treatment plan, including the appropriate medications and dosage, ensuring effective management and improving the patient's quality of life.
Dr. Camel's Conclusion
This study sheds light on the complexities of PAH treatment, emphasizing the importance of individualized care and a stepwise approach to transitioning between medications. By carefully navigating these challenges, healthcare providers can effectively manage PAH and improve the well-being of their patients.
Date :
- Date Completed n.d.
- Date Revised 2022-04-27
Further Info :
Related Literature
English
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