Paper Details
- Home
- Paper Details
Results of a phase I trial to assess the safety of macitentan in combination with temozolomide for the treatment of recurrent glioblastoma.
Author: ManfriniMarianna, Penas-PradoMarta, PuduvalliVinay K, Rood-BreithauptJulie, ThomasGail, WeathersShiao-Pei, YungW K Alfred, ZwingelsteinChristian, de GrootJohn
Original Abstract of the Article :
There is an urgent need for additional therapies to treat recurrent glioblastoma (GBM). Preclinical studies suggest that high dose macitentan, an oral dual endothelin receptor antagonist, enhances the cytotoxic effects of temozolomide (TMZ) in GBM, improving survival. This phase I trial investigated...See full text at original site
Dr.Camel's Paper Summary Blogラクダ博士について
ラクダ博士は、Health Journal が論文の内容を分かりやすく解説するために作成した架空のキャラクターです。
難解な医学論文を、専門知識のない方にも理解しやすいように、噛み砕いて説明することを目指しています。
* ラクダ博士による解説は、あくまで論文の要点をまとめたものであり、原論文の完全な代替となるものではありません。詳細な内容については、必ず原論文をご参照ください。
* ラクダ博士は架空のキャラクターであり、実際の医学研究者や医療従事者とは一切関係がありません。
* 解説の内容は Health Journal が独自に解釈・作成したものであり、原論文の著者または出版社の見解を反映するものではありません。
引用元:
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8528265/
データ提供:米国国立医学図書館(NLM)
Glioblastoma: A New Hope on the Horizon
Glioblastoma, a highly aggressive brain tumor, is a formidable foe in the field of oncology. This research, like a brave warrior venturing into a battle against a formidable enemy, explores the potential of a new combination therapy for recurrent glioblastoma. This study, with its meticulous methodology, seeks to find a new weapon in the fight against this devastating disease.
A New Alliance for a Stronger Fight
The study investigates the safety and efficacy of combining macitentan, an oral dual endothelin receptor antagonist, with temozolomide (TMZ), a chemotherapy drug, in patients with recurrent glioblastoma. It's like forging a new alliance in the desert, combining the strength of two different tribes to defeat a common enemy. This study, like a skilled strategist, explores the potential for this combination therapy to improve survival and quality of life for patients with glioblastoma.
A Glimmer of Hope
This research, like a desert oasis providing a much-needed respite in a harsh environment, offers a glimmer of hope for patients with glioblastoma. It's a reminder that even in the most challenging battles, new strategies and innovations can emerge, offering a brighter future for those fighting for their lives.
Dr.Camel's Conclusion
The research on combining macitentan and temozolomide, like a new oasis discovered in the desert, offers a promising new approach to treating recurrent glioblastoma. It's a testament to the relentless pursuit of innovation in the fight against this devastating disease.
Date :
- Date Completed n.d.
- Date Revised 2022-04-27
Further Info :
Related Literature
English
This site uses cookies. Visit our privacy policy page or click the link in any footer for more information and to change your preferences.