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Effect of Exercise and Quercetin in Rats with Metabolic Syndrome Induced with Fructose.

Author: ErFatmanur, GünayMehmet, KozMitat, PaşaoğluÖzge Tuğçe, TürközkanNurten, YılmazCanan, ZorbaErdal

Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.
Research Support, Non-U.S. Gov'tResearch funding provided by government agencies outside the United States.

Overview

High fructose consumption in rats led to metabolic syndrome (MetS) with increased systolic blood pressure (SBP), triglycerides (TG), VLDL-cholesterol, glucose, insulin, and HOMA-IR. Exercise significantly improved these parameters, while quercetin showed positive effects on SBP and insulin but increased TG and body fat mass.
Paper Details　
Original Abstract of the Article :
<b><i>Background:</i></b> Metabolic syndrome (MetS), one of the most researched topics in recent years, is a metabolic disorder that presents with increased inactivity and has increasing prevalence in the developing world where many ready-made foods are consumed. This research aimed to investigate ...See full text at original site
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引用元：
https://doi.org/10.1089/met.2021.0010

データ提供：米国国立医学図書館（NLM）

Exercise and Quercetin: A Two-Pronged Approach to Metabolic Syndrome

The [metabolic syndrome (MetS)] landscape is a challenging one, characterized by a complex interplay of metabolic disorders. This study, like a camel caravan seeking to overcome adversity, investigates the potential benefits of [exercise] and [quercetin] in a rat model of MetS induced by [fructose]. The study, a carefully designed [experimental study], reveals that both exercise and quercetin can exert positive effects on various MetS-related parameters, but their impact on [lipid profile] varies. This highlights the need for a nuanced approach to managing MetS, with tailored strategies for optimizing individual health outcomes.

Exercise and Quercetin: A Complex Interplay in MetS

The results demonstrate that exercise effectively reduced several MetS-related parameters, including [systolic blood pressure (SBP)], [triglycerides (TG)], [insulin], and [homeostasis model assessment of insulin resistance (HOMA-IR)], while quercetin exhibited positive effects on SBP and insulin levels. However, quercetin also led to a significant increase in TG and body fat mass. This complex interplay underscores the need for careful consideration when implementing these interventions.

A Balanced Approach to MetS: Embracing the Desert's Nuances

The study suggests that a balanced approach to MetS management is essential, incorporating both lifestyle modifications like exercise and potential therapeutic interventions like quercetin. However, it emphasizes the need for further research to optimize the use of quercetin and understand its long-term effects. The desert of MetS is vast and diverse, and a personalized approach is needed to navigate its complexities.

Dr.Camel's Conclusion

This study provides valuable insights into the potential benefits of exercise and quercetin in managing metabolic syndrome. While both interventions showed positive effects on various MetS-related parameters, their impact on lipid profile varied. The study underscores the need for a personalized approach to MetS management, incorporating both lifestyle modifications and potential therapeutic interventions, while recognizing the importance of further research to optimize these strategies.

Date :
  1. Date Completed 2022-04-28
  2. Date Revised 2022-04-28
Further Info :

Pubmed ID

34788565

DOI: Digital Object Identifier

10.1089/met.2021.0010

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Languages

English

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