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Development of a DHA-Losartan hybrid as a potent inhibitor of multiple pathway-induced platelet aggregation.
Author: CholevaMaria, FragopoulouElizabeth, GanaiAb Majeed, KarpoormathRajshekhar, KiriakidiSofia, MavromoustakosThomas, PathaTabasum Khan, TsiailanisAntonis D, TzakosAndreas G, VrettosEirinaios I
Original Abstract of the Article :
Despite the scientific progression in the prevention and treatment of cardiovascular diseases (CVDs) they remain the leading cause of mortality and disability worldwide. The classic treatment involves the simultaneous dosing of two antiplatelet drugs, aspirin and clopidogrel/prasugrel. However, besi...See full text at original site
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引用元:
https://doi.org/10.1080/07391102.2021.1996461
データ提供:米国国立医学図書館(NLM)
A New Hybrid for Fighting Blood Clots: DHA-Losartan
Imagine a desert landscape where a river of blood flows, carrying vital nutrients. But what happens when a clot forms, blocking the flow and causing a dangerous blockage? This research explores a new approach to preventing blood clots, using a powerful hybrid molecule called DHA-Losartan. It’s like creating a new oasis in the desert, offering a safe haven for the river to flow freely.
DHA-Losartan combines the strengths of two well-established components: docosahexaenoic acid (DHA), a fatty acid found in fish oil, and losartan, a drug used to lower blood pressure. DHA is known to inhibit platelet aggregation, like a special barrier preventing the blood cells from clumping together. Losartan, on the other hand, blocks a specific receptor that plays a role in blood clotting. The authors, like skilled desert engineers, combined these two components to create a potent hybrid molecule that effectively targets multiple pathways involved in blood clotting. This is like creating a multi-layered oasis, offering comprehensive protection for the vital flow of blood.
A Multifaceted Approach to Preventing Blood Clots
This research suggests that DHA-Losartan could be a valuable addition to the arsenal for fighting blood clots. Its ability to target multiple pathways involved in platelet aggregation offers a more comprehensive approach to prevention, like creating a network of oases to ensure a safe and continuous flow of blood throughout the body.
Protecting the Cardiovascular System
This research highlights the potential of DHA-Losartan to protect the cardiovascular system from the dangers of blood clots. Its multi-targeted approach could be a valuable tool for preventing heart attacks, strokes, and other cardiovascular events. It’s like building a sturdy dam along the river of blood, preventing dangerous blockages and ensuring a smooth flow of life.
Dr.Camel's Conclusion
DHA-Losartan, a powerful hybrid molecule, offers a promising new approach to preventing blood clots. Its ability to target multiple pathways involved in platelet aggregation makes it a versatile tool for protecting the cardiovascular system. It's like creating a safe and efficient network of oases, ensuring the smooth flow of blood through the desert of our bodies.
Date :
- Date Completed 2022-12-28
- Date Revised 2023-02-28
Further Info :
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