Blood-Brain Barrier in Brain Tumors: Biology and Clinical Relevance.

Author: MoFrancesca, PellerinoAlessia, RudàRoberta, SoffiettiRiccardo

Paper Details 
Original Abstract of the Article :
The presence of barriers, such as the blood-brain barrier (BBB) and brain-tumor barrier (BTB), limits the penetration of antineoplastic drugs into the brain, resulting in poor response to treatments. Many techniques have been developed to overcome the presence of these barriers, including direct inj...See full text at original site
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引用元:
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8657947/

データ提供:米国国立医学図書館(NLM)

Blood-Brain Barrier in Brain Tumors: Biology and Clinical Relevance

The brain, a complex and vital organ, is protected by a formidable barrier called the blood-brain barrier (BBB), which acts as a gatekeeper, carefully controlling the passage of substances into the brain. In the case of brain tumors, however, this barrier becomes a formidable obstacle, limiting the effectiveness of chemotherapy drugs. This research delves into the intricate interplay between the BBB, brain tumor barrier (BTB), and the development of effective treatments for brain tumors, exploring ways to overcome these barriers and improve the delivery of therapeutic agents.

Conquering the Barriers in Brain Tumor Treatment

This research, a journey through the desert of brain tumor treatment, highlights the challenges posed by the BBB and BTB. However, it also reveals promising new strategies for overcoming these barriers, like using direct injections, chemical modifications of drugs, and physical disruption techniques. While these approaches are still under development, they hold the potential to revolutionize the treatment of brain tumors, allowing for more effective delivery of chemotherapy drugs and potentially leading to better outcomes for patients.

Navigating the Complexities of Brain Tumor Treatment

This research underscores the importance of a multifaceted approach to treating brain tumors. By understanding the complexities of the BBB and BTB and developing innovative strategies to overcome these barriers, we can unlock new possibilities for effective treatment. This research is a testament to the ongoing efforts of researchers around the world to develop better treatments for brain tumors, bringing hope to patients and their families.

Dr. Camel's Conclusion

The desert of brain tumor treatment is vast and unforgiving, but this research offers a glimmer of hope. By exploring new strategies to overcome the BBB and BTB, we can forge a path toward more effective treatment options for patients battling this challenging disease.

Date :
  1. Date Completed 2021-12-22
  2. Date Revised 2021-12-22
Further Info :

Pubmed ID

34884457

DOI: Digital Object Identifier

PMC8657947

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Languages

English

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