Administration of Parenteral Vitamin C in Patients With Severe Infection: Protocol for a Systematic Review and Meta-analysis.

Author: AdhikariNeill Kj, AgarwalArnav, BasmajiJohn, CoubanRachel, FaisalHaseeb, FernandoShannon M, GeFang Zhou, HonarmandKimia, HylandsMathieu, LamontagneFrançois, LauVincent I, LewisKimberley, XiaoYingqi

Paper Details 
Original Abstract of the Article :
BACKGROUND: Severe infections are characterized by inflammation and oxidative damage. Ascorbic acid (vitamin C) administration may attenuate oxidative damage and, in turn, reduce vascular endothelial injury in pulmonary and systemic vasculature. OBJECTIVE: We aim to describe a protocol for a living...See full text at original site
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引用元:
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8734609/

データ提供:米国国立医学図書館(NLM)

Parenteral Vitamin C: Exploring the Oasis of Immune Support in Severe Infections

Severe infections, like a raging sandstorm, can overwhelm the body's defenses, leading to serious complications. This study delves into the potential benefits of parenteral vitamin C administration in patients with severe infections, including those with COVID-19. The authors aim to conduct a systematic review and meta-analysis to evaluate the effectiveness and safety of this intervention. They will analyze randomized controlled trials comparing parenteral vitamin C to no vitamin C in hospitalized adults with severe infections. The primary outcome of interest will be mortality, both in-hospital and at 30 and 90 days. This research holds promise for improving outcomes in patients with severe infections, potentially offering a valuable tool for bolstering immune function and enhancing recovery.

Vitamin C: A Potential Oasis in the Desert of Severe Infections

This systematic review aims to investigate the potential benefits of parenteral vitamin C in patients with severe infections. The study's focus on mortality as a primary outcome emphasizes the potential for this intervention to significantly impact patient outcomes, offering hope for improving survival rates and enhancing recovery in this challenging patient population.

Living with Severe Infections: Navigating the Desert with Nutritional Support

This research highlights the importance of exploring potential nutritional interventions for patients with severe infections. The study's focus on vitamin C underscores the need for a comprehensive approach to patient care, considering both medical and nutritional factors. By understanding the potential benefits and risks of vitamin C administration, clinicians can make informed decisions regarding its use, potentially improving patient outcomes and promoting a smoother recovery. Remember, just as a traveler prepares for a desert journey with a well-stocked pack, a comprehensive approach to patient care, including nutritional support, can be crucial for navigating the challenges of severe infections.

Dr.Camel's Conclusion

This systematic review aims to evaluate the effectiveness and safety of parenteral vitamin C administration in patients with severe infections. The study's focus on mortality and other important outcomes holds promise for improving patient outcomes and providing valuable insights into the role of nutritional support in managing severe infections.

Date :
  1. Date Completed n.d.
  2. Date Revised 2022-01-22
Further Info :

Pubmed ID

34910661

DOI: Digital Object Identifier

PMC8734609

Related Literature

SNS
PICO Info
in preparation
Languages

English

Positive IndicatorAn AI analysis index that serves as a benchmark for how positive the results of the study are. Note that it is a benchmark and requires careful interpretation and consideration of different perspectives.

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