Co-encapsulated nanoparticles of Erlotinib and Quercetin for targeting lung cancer through nuclear EGFR and PI3K/AKT inhibition.

Author: AlavalaSateesh, AndugulapatiSai Balaji, BathiniNagendra Babu, ChellaNaveen, GanthalaParimala Devi, SistlaRamakrishna

Paper Details 
Original Abstract of the Article :
Erlotinib-based EGFR targeted therapy has proven significant clinical improvement against non-small cell lung cancer (NSCLC). However, the anticancer activity of Erlotinib (Ertb) is limited by the development of Ertb resistance and possess a challenge to clinicians and patients. To explore a better ...See full text at original site
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引用元:
https://doi.org/10.1016/j.colsurfb.2021.112305

データ提供:米国国立医学図書館(NLM)

Targeting Lung Cancer with Co-Encapsulated Nanoparticles: A New Frontier

Non-small cell lung cancer (NSCLC) is a devastating disease, often characterized by resistance to traditional therapies. It's like a desert fortress, with a resilient enemy protected by a thick wall of resistance. This study explores the potential of co-encapsulated nanoparticles of erlotinib and quercetin for targeting lung cancer, aiming to overcome resistance and improve treatment outcomes.

Breaking Through the Walls: A New Strategy for Lung Cancer

The study found that co-encapsulated nanoparticles of erlotinib and quercetin showed promising results in targeting lung cancer cells. This approach demonstrated a synergistic effect, potentially overcoming resistance mechanisms and improving the efficacy of erlotinib-based therapy. It's like finding a hidden entrance to the fortress, allowing us to bypass the defensive walls and attack the enemy from a new angle.

A New Oasis in the Lung Cancer Desert

The research offers hope for patients battling non-small cell lung cancer, providing a new avenue for targeted and effective therapy. This study highlights the potential of nanotechnology in cancer treatment, a beacon of hope in the desert of this challenging disease. This research represents a significant step forward in the fight against lung cancer, offering a new oasis of hope for patients.

Dr.Camel's Conclusion

The battle against lung cancer is a relentless journey through a vast and unforgiving desert. This research explores a new approach, utilizing co-encapsulated nanoparticles of erlotinib and quercetin, to overcome resistance and improve treatment outcomes. It's a promising strategy, like discovering a hidden wellspring in the desert, offering a potential solution to a challenging problem and providing hope for those affected by this devastating disease.
Date :
  1. Date Completed 2022-02-21
  2. Date Revised 2022-02-21
Further Info :

Pubmed ID

34998178

DOI: Digital Object Identifier

10.1016/j.colsurfb.2021.112305

Related Literature

SNS
PICO Info
in preparation
Languages

English

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