pH-Triggered, Synbiotic Hydrogel Beads for <i>In Vivo</i> Therapy of Iron Deficiency Anemia and Reduced Inflammatory Response.

Author: BhuniaRupam Kumar, GuptaRitika, KaulSunaina, KaurSimranjit, KondepudiKanthi Kiran, SagarPoonam, SharmaShikha, SinghVishal, SinghalNitin Kumar

Paper Details 
Original Abstract of the Article :
Iron deficiency anemia (IDA) is the most common nutritional disorder worldwide nearly affecting two billion people. The efficacies of conventional oral iron supplements are mixed, intravenous iron administration acquaintances with finite but crucial risks. Usually, only 5-20% iron is absorbed in the...See full text at original site
Dr.Camel IconDr.Camel's Paper Summary Blogラクダ博士について

ラクダ博士は、Health Journal が論文の内容を分かりやすく解説するために作成した架空のキャラクターです。
難解な医学論文を、専門知識のない方にも理解しやすいように、噛み砕いて説明することを目指しています。

* ラクダ博士による解説は、あくまで論文の要点をまとめたものであり、原論文の完全な代替となるものではありません。詳細な内容については、必ず原論文をご参照ください。
* ラクダ博士は架空のキャラクターであり、実際の医学研究者や医療従事者とは一切関係がありません。
* 解説の内容は Health Journal が独自に解釈・作成したものであり、原論文の著者または出版社の見解を反映するものではありません。


引用元:
https://doi.org/10.1021/acsabm.1c00720

データ提供:米国国立医学図書館(NLM)

A Synbiotic Hydrogel Approach to Iron Deficiency Anemia

Iron deficiency anemia (IDA), the most common nutritional disorder globally, affects billions of people. While traditional oral iron supplements have mixed efficacy and intravenous iron administration carries risks, researchers continue to seek safer and more effective treatments. This study explores a novel approach using pH-triggered, synbiotic hydrogel beads to deliver iron and probiotics simultaneously, aiming to improve iron absorption and reduce inflammation.

A Novel Approach to Iron Supplementation

The researchers developed hydrogel beads containing iron and probiotics, which are released at intestinal pH, maximizing iron absorption and supporting gut health. They demonstrated the efficacy of this formulation in mitigating IDA in animal models, showing improved iron bioavailability and reduced inflammation compared to conventional iron supplements. This innovative approach combines the benefits of iron supplementation with the positive effects of probiotics, offering a promising strategy for treating IDA.

A Holistic Approach to Gut Health

This research highlights the interconnectedness of iron absorption, gut health, and overall well-being. By promoting a healthy gut microbiome, the synbiotic hydrogel formulation not only enhances iron absorption but also potentially reduces inflammation and improves overall health. This approach underscores the importance of considering the gut microbiome in treating nutritional deficiencies and promoting optimal health.

Dr.Camel's Conclusion

Imagine a vast desert oasis, where the waters are teeming with life and the air is filled with the scent of blooming flowers. This study offers a glimpse into the potential of a synbiotic hydrogel approach to treating iron deficiency anemia, providing a new way to replenish vital nutrients and restore balance to the body. Just as a camel adapts to the harsh desert environment, our bodies constantly strive for equilibrium. This research demonstrates how innovative approaches can harness the power of nature to improve human health and create a more balanced and vibrant life.

Date :
  1. Date Completed 2022-04-08
  2. Date Revised 2022-04-08
Further Info :

Pubmed ID

35006707

DOI: Digital Object Identifier

10.1021/acsabm.1c00720

Related Literature

SNS
PICO Info
in preparation
Languages

English

Positive IndicatorAn AI analysis index that serves as a benchmark for how positive the results of the study are. Note that it is a benchmark and requires careful interpretation and consideration of different perspectives.

This site uses cookies. Visit our privacy policy page or click the link in any footer for more information and to change your preferences.