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Systemic side effects from ophthalmic timolol and their prevention.

Author: FraunfelderF T, MeyerS M

Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.
Research Support, Non-U.S. Gov'tResearch funding provided by government agencies outside the United States.
Research Support, U.S. Gov't, P.H.S.Research funding provided by the Public Health Service (PHS).

Overview

Topical ophthalmic drugs can cause systemic effects due to absorption or metabolic interference. Timolol, a beta-adrenergic blocker, has been associated with significant systemic adverse effects. Various methods to minimize systemic effects, such as avoiding overdosage and proper application techniques, are discussed.
Paper Details　
Original Abstract of the Article :
Topically applied ophthalmic drugs can occasionally produce adverse systemic effects due to systemic absorption of the drug or impediment of the drug's metabolism. Increasing evidence points to significant adverse systemic effects from topical ocular administration of timolol, a beta-adrenergic bloc...See full text at original site
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引用元：
https://doi.org/10.1089/jop.1987.3.177

データ提供：米国国立医学図書館（NLM）

Navigating the Systemic Effects of Topical Timolol

Topical medications, though seemingly localized in their application, can sometimes have unintended systemic effects. This study explores the systemic side effects associated with the topical ophthalmic use of timolol, a beta-adrenergic blocking agent commonly used for glaucoma treatment. The researchers highlight the potential for significant systemic effects due to absorption and metabolic interference. They discuss various methods to minimize or avoid these unwanted effects, including dosage control and proper application techniques.

Understanding the Reach of Topical Medications

This study reminds us that topical medications, despite their localized application, can sometimes have systemic effects. The researchers highlight the potential for significant systemic effects associated with topical timolol, a medication used for glaucoma treatment. This underscores the importance of careful monitoring for any systemic effects and the need for strategies to minimize potential risks. It's like recognizing that even a small desert spring can have a wider impact on the surrounding ecosystem.

The Importance of Awareness in Healthcare

As Dr. Camel, I'm always emphasizing the importance of awareness in healthcare. This study illustrates that even seemingly localized treatments can have broader systemic effects. It's like recognizing that even a small ripple in a desert pool can create larger waves throughout the surrounding terrain. Understanding the potential for systemic effects is crucial for ensuring safe and effective patient care.

Dr.Camel's Conclusion

This study explores the systemic side effects associated with topical ophthalmic use of timolol, a medication used for glaucoma treatment. The researchers highlight the importance of careful monitoring for potential systemic effects and provide valuable insights into strategies for minimizing these risks. This information is crucial for healthcare professionals treating patients with glaucoma, ensuring safe and effective treatment regimens.

Date :
  1. Date Completed 1988-12-20
  2. Date Revised 2019-10-29
Further Info :

Pubmed ID

3503912

DOI: Digital Object Identifier

10.1089/jop.1987.3.177

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Article Analysis
・Side Effects of timolol
SNS
PICO Info
in preparation
Languages

English

Positive IndicatorAn AI analysis index that serves as a benchmark for how positive the results of the study are. Note that it is a benchmark and requires careful interpretation and consideration of different perspectives.

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