Paper Details 
Original Abstract of the Article :
BACKGROUND: We aimed to investigate the long-term effects of tenofovir disoproxil fumarate and entecavir treatment on bone mineral density and evaluated the fracture risk assessment tool score in patients with chronic hepatitis B. METHODS: A total of 58 chronic hepatitis B patients treated with ten...See full text at original site
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引用元:
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9128468/

データ提供:米国国立医学図書館(NLM)

Long-Term Effects of Tenofovir and Entecavir on Bone Health in Chronic Hepatitis B Patients

The world of medicine is like a vast desert, full of mysteries waiting to be unraveled. One such mystery is the long-term impact of certain medications on bone health. This study, much like an intrepid explorer venturing into the desert, delves into the effects of tenofovir disoproxil fumarate and entecavir, two medications used to treat chronic hepatitis B, on bone mineral density. The researchers employed a prospective study, carefully observing 58 patients over several years. Their findings, akin to discovering a hidden oasis, shed light on a potentially significant side effect.

Tenofovir Disoproxil Fumarate: A Potential Impact on Bone Density

The study revealed that tenofovir disoproxil fumarate, while effectively combating hepatitis B, might have a negative impact on bone density, particularly in the lumbar spine. This is like finding that a seemingly refreshing oasis harbors hidden dangers. This discovery underscores the importance of monitoring bone health in patients receiving long-term tenofovir disoproxil fumarate treatment.

Bone Health: A Vital Concern for Hepatitis B Patients

This study, like a compass guiding us through the desert of medical knowledge, points to the importance of comprehensive care for patients with chronic hepatitis B. Monitoring bone density and taking necessary preventative measures, such as adjusting treatment plans or incorporating calcium and vitamin D supplements, can help navigate potential risks and protect bone health. This study encourages us to be mindful of the potential downsides of medication, even those meant to improve health.

Dr.Camel's Conclusion

Just like the desert landscape, the human body is a complex and often unpredictable environment. This study reminds us that even well-intentioned medical interventions can have unintended consequences. By diligently observing and carefully analyzing the effects of medications on bone health, we can ensure that our patients, like camels navigating the desert, remain strong and resilient.

Date :
  1. Date Completed 2022-04-13
  2. Date Revised 2022-07-16
Further Info :

Pubmed ID

35040786

DOI: Digital Object Identifier

PMC9128468

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Languages

English

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