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Primidone Intolerance in Essential tremor: Is it More than Just Age?

Author: LenkaAbhishek, LouisElan D

Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.
Research Support, N.I.H., ExtramuralResearch funding provided by the NIH to external research institutions and researchers.
ReviewAn article that critically examines existing research on a particular topic and summarizes the current state of knowledge in the field.

Overview

Primidone, a medication for essential tremor, is associated with significant adverse drug reactions (ADRs). This study investigates the reasons for variability in ADRs among primidone-treated patients with essential tremor compared to those with epilepsy.
Paper Details　
Original Abstract of the Article :
There are few medications for the treatment of essential tremor (ET). One of these, primidone, which is one of only two front-line agents, is associated with considerable adverse drug reactions (ADRs). It is unclear why some primidone-treated ET patients develop ADRs whereas others do not, and why t...See full text at original site
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引用元：
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8719469/

データ提供：米国国立医学図書館（NLM）

Primidone Intolerance in Essential Tremor: A Camel's Quest for Understanding

Essential tremor (ET) is a neurological condition characterized by involuntary shaking, often affecting the hands and head. While primidone is a potential treatment option for ET, it's associated with significant adverse drug reactions (ADRs). This study delves into the mystery of primidone intolerance in ET patients, exploring the factors that contribute to its occurrence. The authors critically examine the prevalence of ADRs in ET patients compared to those with epilepsy, seeking to understand why primidone seems to be more challenging for ET patients.

Primidone Intolerance: A Puzzle in the Desert of Tremor Research

This research presents a fascinating puzzle in the desert of tremor research. The authors' exploration of primidone intolerance in ET patients provides valuable insights into the complex interplay of factors that influence drug response. Understanding these factors could pave the way for more personalized and effective treatment strategies for ET patients.

Essential Tremor: Navigating a Challenging Landscape

Essential tremor is a challenging condition, often impacting daily activities and quality of life. This study highlights the complexities of treating ET, emphasizing the need for careful consideration of individual patient factors and the potential for ADRs with certain medications. It's important to consult with a healthcare professional to discuss the most suitable treatment approach for your individual needs.

Dr.Camel's Conclusion

The search for effective and safe treatments for essential tremor is a continuous journey. This research sheds light on the complex issue of primidone intolerance in ET patients. By understanding the factors that contribute to ADRs, we can pave the way for more personalized and effective treatment strategies. The desert of tremor research is vast, but with each new discovery, we move closer to a brighter future for ET patients.

Date :
  1. Date Completed 2022-01-26
  2. Date Revised 2022-01-26
Further Info :

Pubmed ID

35070493

DOI: Digital Object Identifier

PMC8719469

Related Literature

Article Analysis
・Side Effects of primidone
SNS
PICO Info
in preparation
Languages

English

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