Efficacy and safety of avanafil as compared with sildenafil in the treatment of erectile dysfunction: A randomized, double blind, multicenter clinical trial.

Author: GoyalSanjay, GuptaS VijayaBhaskara, KumarManish, MittalRavindra, PathadeAmey D, RathDebadarshi, SanmukhaniJayesh, ThakreManish

Paper Details 
Original Abstract of the Article :
OBJECTIVE: To compare the efficacy and safety of avanafil as compared with sildenafil in the management of patients with erectile dysfunction. METHODS: It was a prospective, randomized, double-blind, two-arm, active-controlled, parallel, multicenter, non-inferiority clinical study carried out in pa...See full text at original site
Dr.Camel IconDr.Camel's Paper Summary Blogラクダ博士について

ラクダ博士は、Health Journal が論文の内容を分かりやすく解説するために作成した架空のキャラクターです。
難解な医学論文を、専門知識のない方にも理解しやすいように、噛み砕いて説明することを目指しています。

* ラクダ博士による解説は、あくまで論文の要点をまとめたものであり、原論文の完全な代替となるものではありません。詳細な内容については、必ず原論文をご参照ください。
* ラクダ博士は架空のキャラクターであり、実際の医学研究者や医療従事者とは一切関係がありません。
* 解説の内容は Health Journal が独自に解釈・作成したものであり、原論文の著者または出版社の見解を反映するものではありません。


引用元:
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9303470/

データ提供:米国国立医学図書館(NLM)

Avanafil vs. Sildenafil: A Head-to-Head Comparison for Erectile Dysfunction

Erectile dysfunction (ED) is a common condition that can significantly impact a man's quality of life. This research compares the efficacy and safety of avanafil, a newer medication for ED, with sildenafil, a well-established treatment option. The authors conducted a randomized, double-blind, multicenter clinical trial to assess the effectiveness of both medications in improving erectile function.

A Tale of Two Medications

The study found that avanafil was superior to sildenafil in improving erectile function, as measured by the International Index of Erectile Function (IIEF) score, at the end of 12 weeks of treatment. The researchers also observed that avanafil had a faster onset of action compared to sildenafil. Both medications were well-tolerated by the participants, with headache being the most common side effect reported in both groups.

A New Option for Men with ED

This research provides valuable insights into the relative effectiveness of avanafil and sildenafil for ED. The findings suggest that avanafil offers a promising new treatment option for men with ED, providing an effective and well-tolerated alternative to sildenafil. Further research is needed to explore the long-term safety and efficacy of avanafil and its potential for use in men with specific underlying conditions contributing to ED.

Dr.Camel's Conclusion

Just as a camel navigates the desert with its surefootedness, researchers are navigating the complexities of ED treatment with a comparative analysis of avanafil and sildenafil. The findings suggest that avanafil offers a promising new path towards improving erectile function for men with ED.

Date :
  1. Date Completed 2022-04-07
  2. Date Revised 2022-07-29
Further Info :

Pubmed ID

35080051

DOI: Digital Object Identifier

PMC9303470

Related Literature

Article Analysis
SNS
PICO Info
in preparation
Languages

English

Positive IndicatorAn AI analysis index that serves as a benchmark for how positive the results of the study are. Note that it is a benchmark and requires careful interpretation and consideration of different perspectives.

This site uses cookies. Visit our privacy policy page or click the link in any footer for more information and to change your preferences.