Paper Details 
Original Abstract of the Article :
Several chemicals have been identified as thyroid hormone axis disrupting chemicals (THADCs) able to interfere with the thyroid hormone system during fetal life and early life stages, thereby impairing neurodevelopment in mammals and inducing development and growth disorders in fish and amphibians. ...See full text at original site
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引用元:
https://doi.org/10.1016/j.aquatox.2022.106094

データ提供:米国国立医学図書館(NLM)

Thyroid Hormone Disruptors: A Desert of Development

The delicate balance of the thyroid hormone system is crucial for proper development and growth. This study delves into the world of thyroid hormone axis disrupting chemicals (THADCs), exploring their potential impact on the metamorphosis and thyroid gland histopathology of the European common frog. The authors examine the effects of two model THADCs, sodium perchlorate and 6-propylthiouracil (PTU), on the development of frog tadpoles. It's like observing a desert ecosystem, where the delicate balance of life is vulnerable to external disruptions.

Navigating the Desert of Development: Thyroid Hormone Disruptors and Amphibians

The study found that PTU, a known thyroid disruptor, significantly delayed metamorphosis and affected thyroid gland histopathology in frog tadpoles, even at relatively low concentrations. Sodium perchlorate, however, did not show a significant effect on these endpoints. These findings suggest that different THADCs may have varying levels of impact on amphibian development, highlighting the need for further research to understand their specific effects on different species and stages of development. It's like discovering that different sandstorms have unique effects on the desert landscape, affecting some areas more significantly than others.

Staying Safe in the Desert: Protecting Our Environment

The study underscores the importance of environmental monitoring and research into the potential effects of THADCs on wildlife. It's like being a guardian of the desert, ensuring that the fragile ecosystem is protected from harmful influences. By understanding the impacts of these chemicals, we can take steps to minimize their exposure and protect the health of both humans and wildlife.

Dr. Camel's Conclusion

This study sheds light on the potential effects of thyroid hormone disruptors on amphibian development, highlighting the need for further research to understand the diverse impacts of these chemicals on different species. The study emphasizes the importance of environmental monitoring and responsible chemical management to protect the delicate balance of our ecosystems.

Date :
  1. Date Completed 2022-02-15
  2. Date Revised 2022-02-15
Further Info :

Pubmed ID

35134604

DOI: Digital Object Identifier

10.1016/j.aquatox.2022.106094

Related Literature

SNS
PICO Info
in preparation
Languages

English

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