Paper Details

  1. Home
  2. Paper Details

Immunogenicity of a 5-dose pneumococcal vaccination schedule following allogeneic hematopoietic stem cell transplantation.

Author: Garcia GarridoHannah M, GoorhuisAbraham, GrobuschMartin P, HaggenburgSabine, HazenbergMette D, MeekBob, MeijerEllen, NurErfan, RuttenCaroline E, SchoordijkMarieke C E, TanckMichael W T, de BreeGodelieve J

Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.
Research Support, Non-U.S. Gov'tResearch funding provided by government agencies outside the United States.

Overview

This prospective cohort study investigated the immunogenicity of a 5-dose pneumococcal vaccination schedule in adult allogeneic hematopoietic stem cell transplantation (allo-HSCT) recipients. While the response to PCV13 was reasonable, the response to PPSV23 serotypes was poor, leading to insufficient overall seroprotection. Further research is needed to develop more effective pneumococcal vaccination strategies for allo-HSCT recipients.
Paper Details　
Original Abstract of the Article :
The optimal schedule of pneumococcal vaccination after allogeneic hematopoietic stem cell transplantation (allo-HSCT) remains controversial. The objective of this study was to investigate the immunogenicity of a 5-dose pneumococcal vaccination schedule in adult allo-HSCT recipients with and without ...See full text at original site
Dr.Camel IconDr.Camel's Paper Summary Blogラクダ博士について

ラクダ博士は、Health Journal が論文の内容を分かりやすく解説するために作成した架空のキャラクターです。
難解な医学論文を、専門知識のない方にも理解しやすいように、噛み砕いて説明することを目指しています。

* ラクダ博士による解説は、あくまで論文の要点をまとめたものであり、原論文の完全な代替となるものではありません。詳細な内容については、必ず原論文をご参照ください。
* ラクダ博士は架空のキャラクターであり、実際の医学研究者や医療従事者とは一切関係がありません。
* 解説の内容は Health Journal が独自に解釈・作成したものであり、原論文の著者または出版社の見解を反映するものではありません。


引用元：
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9303771/

データ提供：米国国立医学図書館（NLM）

Navigating the Immune Desert After a Transplant

The world of transplantation is a fascinating journey. After a hematopoietic stem cell transplant, the immune system needs a helping hand to regain its strength. One way to fortify the immune system is through vaccinations, but finding the perfect vaccination schedule is like finding the perfect path through a shifting desert. This research focuses on finding an effective pneumococcal vaccination schedule for patients after a hematopoietic stem cell transplant (allo-HSCT).

A Vaccination Oasis for Transplant Recipients

This study examined the immunogenicity of a 5-dose pneumococcal vaccination schedule in allo-HSCT recipients. While the researchers observed a reasonable response to the 13-valent pneumococcal conjugate vaccine (PCV13), they found a less-than-ideal response to the 23-valent pneumococcal polysaccharide vaccine (PPSV23). The results suggest that further research is needed to find more effective vaccination strategies for this vulnerable patient group.

The Importance of Immunization after a Transplant

After a transplant, the body is vulnerable to infections, making vaccinations crucial. This study highlights the need for continued research to develop better vaccination strategies for transplant recipients, helping them navigate the post-transplant journey with stronger immune defenses.

Dr. Camel's Conclusion

This research underlines the importance of finding effective vaccination strategies for patients after allo-HSCT. The study demonstrates the need for continued research and innovation to ensure the optimal protection of transplant recipients, like a resilient caravan traversing a challenging desert landscape.

Date :
  1. Date Completed 2022-04-07
  2. Date Revised 2022-07-31
Further Info :

Pubmed ID

35147238

DOI: Digital Object Identifier

PMC9303771

Related Literature

Article Analysis
・Effects of pneumococcal polysaccharide vaccine
SNS
PICO Info
in preparation
Languages

English

Positive IndicatorAn AI analysis index that serves as a benchmark for how positive the results of the study are. Note that it is a benchmark and requires careful interpretation and consideration of different perspectives.

This site uses cookies. Visit our privacy policy page or click the link in any footer for more information and to change your preferences.