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Administration of probiotics to healthy volunteers: effects on reactivity of intestinal mucosa and systemic leukocytes.

Author: AhrnéSiv, JeppssonBengt, JohnsonLouis Banka, LinningeCaroline, MolinGöran, PalmquistIngrid, RömeAndrada, SteneChristina

Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.
Randomized Controlled TrialA clinical trial that randomly assigns participants to treatment and control groups to evaluate the effects of an intervention.

Overview

This study aims to investigate how probiotics, beneficial bacteria taken orally, affect the immune system both throughout the body and specifically in the lining of the rectum. The study will examine the effects of probiotics on immune cells and the rectal lining in response to inflammation. The goal is to better understand how these bacteria work.
Paper Details　
Original Abstract of the Article :
Oral administration of health-promoting bacteria is increasingly used in clinical practise. These bacteria have anti-inflammatory characteristics and modulate the immune system without major reported side effects. The mechanisms of action are not yet fully defined. Our aim was to study systemic effe...See full text at original site
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引用元：
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8898528/

データ提供：米国国立医学図書館（NLM）

Probiotics: Exploring the Untapped Potential of Gut Microbes

The human gut is a complex ecosystem teeming with billions of bacteria, and understanding this intricate world is a constant endeavor. This study focuses on probiotics, which are live bacteria that can benefit our health. The research aims to delve into the systemic and local effects of probiotics on the human body. By utilizing a combination of in vitro and in vivo methods, the researchers investigated the impact of probiotics on leukocytes and rectal mucosal biopsies after introducing an inflammatory stimulus. This research provides valuable insights into the mechanisms by which probiotics may influence the immune system and potentially contribute to overall health.

Probiotics: A Potential Ally in Modulating the Immune System

This research suggests that probiotics have the potential to modulate the immune system, both locally and systemically. By influencing leukocyte activity and the response of rectal mucosal biopsies, probiotics may play a role in regulating inflammation and promoting immune balance. However, further studies are needed to fully elucidate the mechanisms involved and to determine the optimal dosages and types of probiotics for specific health outcomes.

Probiotics: A Potential Pathway to Better Gut Health

The research highlights the growing importance of understanding the gut microbiome and its role in overall health. Probiotics, with their potential to modulate the immune system and influence gut health, offer a promising avenue for promoting well-being. It's essential to approach probiotics with a balanced perspective, acknowledging that further research is needed to fully understand their benefits and potential risks.

Dr.Camel's Conclusion

This research provides a fascinating glimpse into the potential of probiotics to influence the immune system and potentially contribute to better gut health. While further research is needed, the study's findings encourage us to continue exploring the vast and intricate world of the gut microbiome and its role in our overall well-being.
Date :
  1. Date Completed 2022-03-08
  2. Date Revised 2022-03-18
Further Info :

Pubmed ID

35247974

DOI: Digital Object Identifier

PMC8898528

Related Literature

Article Analysis
・Effective treatment of probiotics
SNS
PICO Info
in preparation
Languages

English

Positive IndicatorAn AI analysis index that serves as a benchmark for how positive the results of the study are. Note that it is a benchmark and requires careful interpretation and consideration of different perspectives.

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