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Multiple myeloma in central Norway 1981-1982: a randomized clinical trial of 5-drug combination therapy versus standard therapy.

Author: BjarkP, BondevikA, BullO, DehliO, Kildahl-AndersenO, KvambeV, LamvikJ, NordahlE, YtrehusK

Clinical TrialA clinical trial is a planned study conducted on humans to evaluate the efficacy and safety of pharmaceuticals, medical devices, and treatment methods. It aims to explore the possibilities of new treatments and improve the health of patients.
Comparative StudyResearch that compares multiple groups/interventions to determine differences/similarities in outcomes/characteristics.
Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.
Randomized Controlled TrialA clinical trial that randomly assigns participants to treatment and control groups to evaluate the effects of an intervention.
Research Support, Non-U.S. Gov'tResearch funding provided by government agencies outside the United States.

Overview

A study of 67 patients with multiple myeloma found that both 2-drug and 5-drug combination chemotherapy regimens were effective in achieving remission and had similar survival times. Maintenance therapy did not improve outcomes.
Paper Details　
Original Abstract of the Article :
67 previously untreated patients with multiple myeloma were entered on a randomized clinical trial to determine whether the use of combination chemotherapy including vincristine, carmustine, alkylating agents, and prednisone was more effective than conventional therapy with melphalan and prednisone....See full text at original site
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引用元：
https://doi.org/10.1111/j.1600-0609.1986.tb02304.x

データ提供：米国国立医学図書館（NLM）

Multiple Myeloma Treatment: A Battle in the Desert of Cancer

In the harsh and unforgiving landscape of cancer, multiple myeloma stands as a formidable foe, demanding innovative and effective treatment strategies. This randomized clinical trial, like a well-planned military campaign in the desert, investigates the effectiveness of a 5-drug combination therapy compared to standard therapy for previously untreated patients with multiple myeloma. The authors seek to determine whether the addition of vincristine, carmustine, and alkylating agents to the conventional melphalan and prednisone regimen offers a significant advantage.

A New Approach: A Potential Oasis in Multiple Myeloma Treatment

The study's findings, like a hidden oasis in the desert, suggest that the 5-drug combination therapy may offer a promising treatment option for multiple myeloma. The authors, like skilled strategists, meticulously analyze the data, revealing that the 5-drug combination therapy achieves similar remission rates and median survival compared to the standard therapy. These results, like a beacon of hope in the desert, indicate the potential for this new approach to improve treatment outcomes for multiple myeloma patients.

Navigating the Desert of Cancer Treatment: A Quest for Effective Therapies

The implications of this study are significant for the field of multiple myeloma treatment. It highlights the ongoing quest for more effective therapies and the importance of exploring new treatment regimens to improve outcomes for patients battling this challenging disease. The study, like a map leading to a safe haven in the desert, offers valuable insights into the potential benefits of a 5-drug combination therapy, encouraging further research and development in this area.

Dr. Camel's Conclusion

This randomized clinical trial, like a meticulously planned expedition through the desert of cancer treatment, offers valuable insights into the potential benefits of a 5-drug combination therapy for multiple myeloma. The authors' findings, like a hidden oasis in the vast and challenging landscape of cancer, provide a promising direction for future research and development.
Date :
  1. Date Completed 1986-12-29
  2. Date Revised 2019-09-08
Further Info :

Pubmed ID

3538367

DOI: Digital Object Identifier

10.1111/j.1600-0609.1986.tb02304.x

Related Literature

Article Analysis
・Effective treatment of multiple myeloma
SNS
PICO Info
in preparation
Languages

English

Positive IndicatorAn AI analysis index that serves as a benchmark for how positive the results of the study are. Note that it is a benchmark and requires careful interpretation and consideration of different perspectives.

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