Chlorpheniramine poisoning as a potential cause of rhabdomyolysis.

Author: GuoQingqing, LinHao, LinJiandong

Paper Details 
Original Abstract of the Article :
Chlorpheniramine is an H1 receptor antagonist of the alkylamine class. It is a widely used anti-allergy drug due to its strong antihistamine effect and mild adverse effects. In the case of chlorpheniramine overdose or poisoning, the primary manifestation is central nervous system symptoms. To date, ...See full text at original site
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引用元:
https://doi.org/10.1016/j.ajem.2022.04.010

データ提供:米国国立医学図書館(NLM)

Unveiling a Hidden Danger: Chlorpheniramine and Rhabdomyolysis

Chlorpheniramine, a commonly used antihistamine, is often seen as a safe and effective treatment for allergies. However, a recent case report unveils a previously unknown side effect of this medication - rhabdomyolysis. This study describes a patient who experienced severe rhabdomyolysis after ingesting an exceptionally high dose of chlorpheniramine. This case highlights the potential for this drug to cause significant muscle damage, a finding that could lead to important changes in how we manage and prescribe this medication.

Rhabdomyolysis: A Silent Threat

Rhabdomyolysis is a serious condition characterized by the breakdown of muscle tissue. It can lead to kidney damage and even death. This case report underscores the importance of being aware of the potential for unexpected side effects, even with commonly used medications. The patient's experience serves as a stark reminder that we must remain vigilant in monitoring for adverse effects and seeking appropriate treatment if necessary.

Staying Informed: A Crucial Step Towards Safety

This finding underscores the importance of keeping abreast of the latest research and being aware of potential side effects of medications, even those considered safe. It's crucial to have open communication with your healthcare providers and to report any unusual symptoms or side effects you may experience. By remaining vigilant and proactive, we can help ensure our own safety and well-being.

Dr. Camel's Conclusion

This report, like a sudden sandstorm, reminds us that even in seemingly calm landscapes, hidden dangers can lurk. It's important to approach any medication with a critical eye and to be attentive to any unusual reactions. We need to be aware of the potential for unexpected side effects and seek prompt medical attention if necessary. Just as we navigate the desert with caution, we must approach healthcare with a similar mindset - alert, informed, and prepared for the unexpected.

Date :
  1. Date Completed 2022-06-03
  2. Date Revised 2022-07-13
Further Info :

Pubmed ID

35459564

DOI: Digital Object Identifier

10.1016/j.ajem.2022.04.010

Related Literature

SNS
PICO Info
in preparation
Languages

English

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