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Goofballing of Opioid and Methamphetamine: The Science Behind the Deadly Cocktail.

Author: AbdulrahmanSundus Mansoor, HazaniHanis Mohammad, KamaluddinMohammad Rahim, KumarJaya, Mohamad IsaMohd Fadzli, MohamedWael, MuzaimiMustapha, Naina MohamedIsa, Pakri MohamedRashidi Mohamed, RamadahRavi, TeohSeong Lin, YahayaMohamad Fairuz

Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.
ReviewAn article that critically examines existing research on a particular topic and summarizes the current state of knowledge in the field.

Overview

This review discusses the behavioral, neuroanatomical, and neurochemical changes underlying morphine and methamphetamine dependence, both individually and in combination. The combined use of these drugs has more severe effects than either drug alone, highlighting the importance of addressing polydrug abuse in treatment.
Paper Details　
Original Abstract of the Article :
Globally, millions of people suffer from various substance use disorders (SUD), including mono-and polydrug use of opioids and methamphetamine. Brain regions such as the cingulate cortex, infralimbic cortex, dorsal striatum, nucleus accumbens, basolateral and central amygdala have been shown to play...See full text at original site
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引用元：
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9021401/

データ提供：米国国立医学図書館（NLM）

The Devastating Consequences of Combining Opioids and Methamphetamine

This review delves into the complex realm of addiction and neurobiology, focusing on the combined effects of opioids and methamphetamine. The researchers examine the neuroanatomical and neurochemical changes associated with the co-use of these drugs, highlighting the devastating consequences of this dangerous combination. They emphasize the increased risk of addiction, overdose, and various psychopathologies associated with polydrug use, underscoring the need for effective treatment strategies for individuals struggling with substance use disorders.

The Neuroscience of Polydrug Abuse

This review provides valuable insights into the neurological underpinnings of polydrug abuse, specifically focusing on the combined effects of opioids and methamphetamine. The findings highlight the complex interplay between these drugs and the brain, explaining the increased vulnerability to addiction and the potentially severe consequences of this dangerous combination.

Addressing the Growing Challenge of Polydrug Abuse

The review underscores the urgency of addressing the growing problem of polydrug abuse, particularly the combination of opioids and methamphetamine. The research emphasizes the need for effective treatment strategies that address the unique challenges associated with polydrug use, potentially reducing the devastating consequences of this harmful combination.

Dr.Camel's Conclusion

Just as a camel faces the dangers of a treacherous desert, individuals struggling with polydrug abuse navigate a perilous path. This review provides a glimpse into the neurological complexities of this harmful combination, highlighting the devastating consequences of opioid and methamphetamine co-use. It's a reminder that addressing this growing challenge requires a multi-faceted approach, providing support and effective treatments to help individuals break free from the clutches of addiction.

Date :
  1. Date Completed n.d.
  2. Date Revised 2022-07-16
Further Info :

Pubmed ID

35462918

DOI: Digital Object Identifier

PMC9021401

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・Side Effects of methamphetamine
SNS
PICO Info
in preparation
Languages

English

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