Lasmiditan for Patients with Migraine and Contraindications to Triptans: A Post Hoc Analysis.

Author: BayganiSimin K, KomoriMika, KregeJohn H, LiptonRichard B, RyanSinéad M, VincentMaurice

Paper Details 
Original Abstract of the Article :
Label="INTRODUCTION" NlmCategory="BACKGROUND">As 5-HT<sub>1B</sub> receptor agonists, triptans produce vasoconstriction and have cardiovascular contraindications and precautions. Lasmiditan, a selective 5-HT<sub>1F</sub> receptor agonist, has a low affinity for 5-HT<sub>1B</sub> receptors, does not ...See full text at original site
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引用元:
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9098729/

データ提供:米国国立医学図書館(NLM)

Lasmiditan: A New Hope for Migraine Treatment

Migraine headaches, a debilitating condition characterized by severe throbbing pain, are a common ailment that can significantly impact quality of life. Triptans, a class of drugs often used to treat migraine, can be effective but have limitations, including cardiovascular contraindications. This study investigates the potential of lasmiditan, a novel migraine medication, as an alternative for patients who cannot take triptans.

The researchers examined the efficacy and safety of lasmiditan in patients with and without triptan contraindications. They found that lasmiditan, unlike triptans, does not cause vasoconstriction, making it a safer option for patients with cardiovascular issues. The researchers concluded that lasmiditan was an effective and safe treatment for migraine, even in patients who could not take triptans.

A Promising Alternative for Migraine Treatment

The study suggests that lasmiditan could be a valuable alternative for patients with migraine who cannot take triptans due to cardiovascular contraindications. Lasmiditan's lack of vasoconstrictive effects makes it a safer option for these individuals.

Relief from Migraine without Cardiovascular Concerns

For patients struggling with migraine and cardiovascular concerns, lasmiditan offers a ray of hope. This novel medication provides effective relief from migraine symptoms without the cardiovascular risks associated with triptans.

Dr. Camel's Conclusion

This research explores the potential of lasmiditan as a safe and effective treatment for migraine, particularly for patients with cardiovascular concerns. Like a desert oasis offering relief from the scorching sun, lasmiditan provides a much-needed respite for those who cannot tolerate triptans. This research highlights the importance of developing alternative migraine treatments, offering a new avenue for safe and effective migraine management.

Date :
  1. Date Completed n.d.
  2. Date Revised 2022-07-16
Further Info :

Pubmed ID

35471625

DOI: Digital Object Identifier

PMC9098729

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English

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