Paper Details
- Home
- Paper Details
Effects of imatinib on glycemic and lipid profiles: a retrospective cohort study.
Author: DavidSara, FriedrichCarmel, GuetaItai, HalkinHillel, KurnikDaniel, LoebsteinRonen, LomnickyYossi, MarkovitsNoa, TiroshAmir, TopolYael
Original Abstract of the Article :
Despite a favorable effect of imatinib on glucose metabolism in animal models, human reports are inconsistent. We retrospectively studied the long-term effect of imatinib on fasting plasma glucose (FPG), glycated hemoglobin (HbA1C), LDL-cholesterol (LDL), and triglycerides (TGs) in a large HMO cohor...See full text at original site
Dr.Camel's Paper Summary Blogラクダ博士について
ラクダ博士は、Health Journal が論文の内容を分かりやすく解説するために作成した架空のキャラクターです。
難解な医学論文を、専門知識のない方にも理解しやすいように、噛み砕いて説明することを目指しています。
* ラクダ博士による解説は、あくまで論文の要点をまとめたものであり、原論文の完全な代替となるものではありません。詳細な内容については、必ず原論文をご参照ください。
* ラクダ博士は架空のキャラクターであり、実際の医学研究者や医療従事者とは一切関係がありません。
* 解説の内容は Health Journal が独自に解釈・作成したものであり、原論文の著者または出版社の見解を反映するものではありません。
引用元:
https://doi.org/10.1080/10428194.2022.2068003
データ提供:米国国立医学図書館(NLM)
Imatinib: A Double-Edged Sword? Exploring Its Metabolic Effects
The field of [cancer treatment] is constantly seeking therapies that are both effective and well-tolerated by patients. This study examines the long-term effects of [imatinib], a targeted therapy used to treat certain types of cancer, on [glucose metabolism] and [lipid profiles] in a large cohort of patients.
Imatinib's Metabolic Effects: A Double-Edged Sword
The authors, like explorers venturing into a complex desert landscape, found that imatinib, like a double-edged sword, had both beneficial and potentially detrimental effects on metabolism. While imatinib significantly reduced [HbA1c], [FPG], [LDL], and [TG] levels in the study cohort, these effects, like a desert mirage, require careful consideration in the context of individual patients.
Imatinib's Impact: A Cautionary Tale for Clinicians
This study, like a desert traveler navigating shifting sands, highlights the need for careful monitoring of metabolic parameters in patients receiving imatinib. While imatinib offers potential metabolic benefits, its impact on individual patients, like a desert oasis that may or may not be truly life-sustaining, must be carefully assessed.
Dr. Camel's Conclusion
This study, like a camel caravan traversing a vast and unforgiving desert, reveals the complex interplay between imatinib and metabolic parameters. Imatinib, like a desert mirage that appears both promising and deceptive, requires careful consideration in the context of individual patients. This research, like a compass guiding explorers through a challenging landscape, emphasizes the importance of vigilant monitoring and individualized care in managing the metabolic impact of imatinib therapy.
Date :
- Date Completed 2022-10-10
- Date Revised 2022-12-22
Further Info :
Related Literature
English
This site uses cookies. Visit our privacy policy page or click the link in any footer for more information and to change your preferences.