A Rare Case of Levetiracetam-Induced Refractory Hypokalemia.

Author: CoughlinPaige, PanditRamesh, PatelGoonja, VadakethJessica

Paper Details 
Original Abstract of the Article :
Levetiracetam is a Food and Drug Administration (FDA)-approved drug for partial, generalized, and myoclonic seizures. Its mechanism of action as an antiepileptic involves the release of neurotransmitters from synaptic vesicles. The common side effects of levetiracetam include sleepiness, weakness, d...See full text at original site
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引用元:
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9067888/

データ提供:米国国立医学図書館(NLM)

Levetiracetam and Hypokalemia: A Rare Case Report

This case report delves into the rare and intriguing connection between the antiepileptic drug levetiracetam and refractory hypokalemia. The study presents the case of a 73-year-old woman who developed severe hypokalemia after starting levetiracetam, a condition that proved resistant to multiple repletion attempts. The patient's potassium levels only returned to normal after switching to a different antiepileptic medication, lacosamide. This case report highlights the importance of considering levetiracetam as a potential cause of refractory hypokalemia, reminding us that even common medications can have unexpected side effects. It's like discovering a hidden, prickly cactus in a seemingly harmless desert garden.

The Importance of Vigilance in Monitoring Drug Side Effects

This case study serves as a reminder to healthcare professionals to be vigilant in monitoring patients for potential side effects of medications, even those considered safe and commonly prescribed. The patient's experience underscores the importance of thorough evaluation and timely intervention when unexpected complications arise.

Managing Seizures Safely

This study sheds light on the need for careful consideration of alternative treatment options for epilepsy, especially when patients experience persistent side effects from medications. The patient's successful response to lacosamide highlights the importance of personalized medicine and finding the right treatment approach for each individual.

Dr.Camel's Conclusion

This case report reminds us that even in the vast desert of medical knowledge, surprises can arise. The discovery of a connection between levetiracetam and refractory hypokalemia emphasizes the need for constant vigilance and ongoing research to ensure the safety and efficacy of medications.

Date :
  1. Date Completed n.d.
  2. Date Revised 2022-05-10
Further Info :

Pubmed ID

35530900

DOI: Digital Object Identifier

PMC9067888

Related Literature

SNS
PICO Info
in preparation
Languages

English

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