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Effects of Apremilast on Induced Hypertrophic Scar of Rabbits.
Author: Nidhal GhazyD, Rahmah Abu-RaghifA
Original Abstract of the Article :
The present study aimed to assess the effect of Apremilast on experimentally induced hypertrophic scars in rabbits. A total of 40 healthy male New Zealand White rabbits between 6 and 12 months of age were assigned to four groups (n=10). Group I consists of apparently healthy control rabbit...See full text at original site
Dr.Camel's Paper Summary Blogラクダ博士について
ラクダ博士は、Health Journal が論文の内容を分かりやすく解説するために作成した架空のキャラクターです。
難解な医学論文を、専門知識のない方にも理解しやすいように、噛み砕いて説明することを目指しています。
* ラクダ博士による解説は、あくまで論文の要点をまとめたものであり、原論文の完全な代替となるものではありません。詳細な内容については、必ず原論文をご参照ください。
* ラクダ博士は架空のキャラクターであり、実際の医学研究者や医療従事者とは一切関係がありません。
* 解説の内容は Health Journal が独自に解釈・作成したものであり、原論文の著者または出版社の見解を反映するものではありません。
引用元:
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9083860/
データ提供:米国国立医学図書館(NLM)
Apremilast: A Potential Remedy for the Scars of Time
Hypertrophic scars, those raised, unsightly reminders of past injuries, are a common concern. This research, like a desert explorer mapping new terrain, investigates the potential of Apremilast, a drug already used for psoriasis, as a treatment for these stubborn scars.
The study, conducted on rabbits, employs an experimental model of hypertrophic scars, creating a controlled environment to observe the effects of Apremilast. The researchers meticulously examine the scars' morphology, assessing inflammation, fibroblast activity, and collagen levels. They find that Apremilast, like a skilled desert sculptor, helps to sculpt the scars, reducing inflammation and fibroblast count, effectively diminishing the scar's prominence.
Apremilast's Promising Potential
The research demonstrates that Apremilast, like a skilled desert sculptor, can help to sculpt the scars, reducing inflammation and fibroblast count, effectively diminishing the scar's prominence. The results, like a desert oasis, offer hope for patients seeking a more aesthetically pleasing outcome after injury or surgery.
A Note of Caution and Hope
While the study paints a promising picture for Apremilast's potential, more research is needed to assess its effectiveness in humans and to optimize its dosage. However, the research offers hope for a future where the scars of time can be minimized, leaving behind a smoother, more confident landscape.
Dr.Camel's Conclusion
This study suggests that Apremilast may hold promise as a novel therapeutic agent for hypertrophic scars. Its ability to effectively reduce inflammation and fibroblast activity is encouraging, hinting at a future where the scars of our past may be less prominent, leaving us with a smoother and more confident exterior.
Date :
- Date Completed 2023-06-13
- Date Revised 2023-06-13
Further Info :
Related Literature
English
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