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Evaluation of suvorexant for trauma-related insomnia.

Author: BirkuKiya, KobayashiIhori, LavelaPewu, MellmanThomas A, SandhuIshaan

Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.
Randomized Controlled TrialA clinical trial that randomly assigns participants to treatment and control groups to evaluate the effects of an intervention.
Research Support, Non-U.S. Gov'tResearch funding provided by government agencies outside the United States.

Overview

This study evaluated the efficacy of suvorexant, a dual orexin receptor antagonist (DORA), for trauma-related insomnia in a double-blind, placebo-controlled clinical trial. The study found that suvorexant treatment improved sleep quality and reduced sleep disturbances, with the potential for enhanced REMS while reducing arousal, in contrast to traditional psychotropic agents.
Paper Details　
Original Abstract of the Article :
Effective pharmacological treatments for sleep disturbance related to trauma with and without co-occurring posttraumatic stress disorder (PTSD) are needed. There is debate regarding what effects on rapid eye movement sleep (REMS) would be beneficial. Suvorexant is the first dual orexin receptor anta...See full text at original site
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引用元：
https://doi.org/10.1093/sleep/zsac068

データ提供：米国国立医学図書館（NLM）

Suvorexant for Trauma-Related Insomnia: A New Hope in the Desert of Sleep

The realm of sleep research is often a quest to unravel the secrets of a restful night. Trauma-related insomnia, a common consequence of traumatic experiences, poses a particular challenge. This study explores the potential of suvorexant, a novel medication, in addressing this debilitating condition. Like a traveler seeking shelter in a desert oasis, researchers are searching for effective treatments to alleviate the suffering caused by trauma-related insomnia.

Suvorexant: A New Oasis in the Desert of Sleep

Suvorexant, a dual orexin receptor antagonist (DORA), represents a promising development in the treatment of insomnia. It's like discovering a new and refreshing spring in a barren desert – offering hope and a chance for renewal. The study evaluated suvorexant's efficacy in a double-blind, placebo-controlled clinical trial, assessing its impact on sleep quality and rapid eye movement (REM) sleep.

A Multifaceted Approach: Addressing the Complexities of Trauma

This research highlights the importance of a multifaceted approach to treating trauma-related insomnia. The study examines the potential of suvorexant, a medication, in combination with other therapies, to address the underlying trauma and improve sleep quality. It's like recognizing that a journey through a vast desert requires a combination of skills, resources, and resilience.

Dr. Camel's Conclusion

This study offers a glimmer of hope for those struggling with trauma-related insomnia. It demonstrates the potential of suvorexant as a valuable tool in the fight against this challenging condition. Further research is needed to fully understand its long-term effects and optimize its use.

Date :
  1. Date Completed 2022-05-17
  2. Date Revised 2023-09-20
Further Info :

Pubmed ID

35554590

DOI: Digital Object Identifier

10.1093/sleep/zsac068

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・Side Effects of suvorexant
SNS
PICO Info
in preparation
Languages

English

Positive IndicatorAn AI analysis index that serves as a benchmark for how positive the results of the study are. Note that it is a benchmark and requires careful interpretation and consideration of different perspectives.

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