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Retrospective Analysis of the Use of Tiludronate in Equine Practice: Safety on 1804 Horses, Efficacy on 343 Horses.

Author: AllenKent, DenoixJean-Marie, MitchellRichard D, ParkinTim, TischmacherAdeline, WilfordSophie

Research Support, Non-U.S. Gov'tResearch funding provided by government agencies outside the United States.
Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.

Overview

This retrospective study assessed the safety and efficacy of tiludronate in a large number of horses. Tiludronate, administered intravenously at a dose of 1mg/kg, showed excellent tolerance with only 0.9% of injections causing mild side effects. Clinical follow-up over a year indicated a significant improvement in lameness scores, with over 80% of horses presenting an initial lameness score over 1.5/5 and approximately half becoming sound by 30 days and remaining so after a year. Additionally, performance data demonstrated that 69% of horses were still competing one year after treatment, with 82% of those competing at a better or similar level.
Paper Details　
Original Abstract of the Article :
The objective of this retrospective study was to assess the safety and efficacy of a slow IV administration of 1mg/kg tiludronate in a large number of horses. Each horse that received at least one tiludronate-based treatment between 2006 and August 2019 at Virginia Equine Imaging or Fairfield Equine...See full text at original site
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引用元：
https://doi.org/10.1016/j.jevs.2022.104007

データ提供：米国国立医学図書館（NLM）

Tiludronate for Equine Bone Health

This research explores the use of tiludronate, a bisphosphonate, in horses, a field as vast and fascinating as the Sahara Desert. This retrospective study analyzed data from over 1800 horses treated with tiludronate over 13 years. The researchers aimed to assess the safety and efficacy of tiludronate in treating equine lameness caused by bone conditions. They found that tiludronate was well-tolerated, with only a small percentage of horses experiencing mild side effects. Importantly, the study found that tiludronate was effective in improving lameness and allowing many horses to return to their previous performance levels. It's like a wise desert nomad sharing their knowledge of medicinal plants, revealing the benefits of tiludronate in restoring equine bone health.

A Safe and Effective Oasis

This research offers hope for horses suffering from bone-related lameness. The findings suggest that tiludronate can be a safe and effective treatment option, improving lameness and allowing many horses to return to their previous performance levels. It's like a wise desert nomad sharing their knowledge of medicinal plants, revealing the benefits of tiludronate in restoring equine bone health.

Restoring the Strength of the Desert Camel

Bone conditions can severely impair a horse's ability to function, impacting their athletic performance and overall well-being. This study highlights the potential of tiludronate in addressing these challenges, offering a path towards recovery and restoring the strength and mobility of these magnificent animals. It's like providing a camel with a nourishing oasis, allowing it to regain its strength and continue its journey across the vast desert.

Dr.Camel's Conclusion

This research explores the use of tiludronate, a bisphosphonate, in horses, a field as vast and fascinating as the Sahara Desert. The findings suggest that tiludronate can be a safe and effective treatment option, improving lameness and allowing many horses to return to their previous performance levels. It's like a wise desert nomad sharing their knowledge of medicinal plants, revealing the benefits of tiludronate in restoring equine bone health.

Date :
  1. Date Completed 2022-07-12
  2. Date Revised 2022-09-29
Further Info :

Pubmed ID

35577109

DOI: Digital Object Identifier

10.1016/j.jevs.2022.104007

SNS
PICO Info
in preparation
Languages

English

Positive IndicatorAn AI analysis index that serves as a benchmark for how positive the results of the study are. Note that it is a benchmark and requires careful interpretation and consideration of different perspectives.

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