Comparative evaluation of morphine, pentazocine and ciramadol in postaddicts.

Author: BigelowG E, LiebsonI A, PrestonK L

Paper Details 
Original Abstract of the Article :
The subjective, physiological and behavioral effects of morphine, pentazocine and ciramadol, an opioid agonist/antagonist, were studied in adult male nondependent opioid abusers living on a clinical research ward. Fifteen subjects were assigned randomly to one of three groups. Each group received, b...See full text at original site
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引用元:
https://pubmed.ncbi.nlm.nih.gov/3559982

データ提供:米国国立医学図書館(NLM)

Morphine, Pentazocine, and Ciramadol: A Comparative Study of Opioid Effects

The realm of pain management is a complex one, filled with a myriad of drugs that work in different ways to alleviate suffering. This study delves into the subjective, physiological, and behavioral effects of three opioid drugs - morphine, pentazocine, and ciramadol - on adult male opioid abusers. The researchers meticulously measured various physiological and subjective responses to these drugs, comparing their effects and seeking to understand their unique characteristics. The study's results reveal distinct profiles for each drug, highlighting the complex nature of opioid effects and the need for careful consideration in prescribing these medications.

Unveiling the Desert of Opioid Effects: A Detailed Analysis

The researchers found that all three drugs produced a range of physiological effects, such as decreased respiratory rate and pupil diameter, and increased blood pressure. However, their subjective effects varied significantly, with morphine and ciramadol producing more positive effects, while pentazocine led to a greater increase in negative subjective experiences. The study also observed significant behavioral changes after morphine and pentazocine administration, but not after ciramadol. These findings highlight the nuanced differences between these drugs, emphasizing the importance of careful selection and monitoring when treating patients.

Navigating the Desert: Understanding the Risks and Benefits of Opioid Use

This research highlights the potential risks and benefits associated with the use of opioids. While these drugs can offer relief from pain, they also carry a risk of addiction and adverse side effects. The study's findings underscore the importance of individualizing treatment plans and carefully monitoring patients' responses to opioid medications. It's a reminder that navigating the desert of pain management requires both knowledge and caution.

Dr. Camel's Conclusion

This research provides valuable insights into the multifaceted nature of opioid effects. It emphasizes the importance of understanding the distinct profiles of these drugs to ensure safe and effective pain management. It's a reminder that navigating the desert of opioid treatment requires a comprehensive approach, taking into account individual patient needs and carefully monitoring their responses.

Date :
  1. Date Completed 1987-04-27
  2. Date Revised 2015-11-19
Further Info :

Pubmed ID

3559982

DOI: Digital Object Identifier

3559982

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