Paper Details

  1. Home
  2. Paper Details

Repurposing Dimethyl Fumarate for Cardiovascular Diseases: Pharmacological Effects, Molecular Mechanisms, and Therapeutic Promise.

Author: JhaNiraj Kumar, OjhaShreesh, SadekBassem, ThomasShilu Deepa

Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.
ReviewAn article that critically examines existing research on a particular topic and summarizes the current state of knowledge in the field.

Overview

This review focuses on dimethyl fumarate (DMF), a potent immunoregulatory and anti-inflammatory agent, and its potential applications in cardiovascular diseases. DMF's mechanism of action and its clinical use in treating multiple sclerosis and psoriasis are discussed. Due to its anti-inflammatory and vasculoprotective effects, DMF holds promise as a therapeutic agent for atherosclerotic cardiovascular disease, but further research in larger clinical trials is needed to confirm its long-term cardiovascular benefits.
Paper Details　
Original Abstract of the Article :
Dimethyl fumarate (DMF) is a small molecule that has been shown to assert potent in vivo immunoregulatory and anti-inflammatory therapeutic actions. The drug has been approved and is currently in use for treating multiple sclerosis and psoriasis in the USA and Europe. Since inflammatory reactions ha...See full text at original site
Dr.Camel IconDr.Camel's Paper Summary Blogラクダ博士について

ラクダ博士は、Health Journal が論文の内容を分かりやすく解説するために作成した架空のキャラクターです。
難解な医学論文を、専門知識のない方にも理解しやすいように、噛み砕いて説明することを目指しています。

* ラクダ博士による解説は、あくまで論文の要点をまとめたものであり、原論文の完全な代替となるものではありません。詳細な内容については、必ず原論文をご参照ください。
* ラクダ博士は架空のキャラクターであり、実際の医学研究者や医療従事者とは一切関係がありません。
* 解説の内容は Health Journal が独自に解釈・作成したものであり、原論文の著者または出版社の見解を反映するものではありません。


引用元：
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9143321/

データ提供：米国国立医学図書館（NLM）

Dimethyl Fumarate for Cardiovascular Disease: A Camel's Journey to Heart Health

This research explores the potential of dimethyl fumarate (DMF), a drug currently used for multiple sclerosis and psoriasis, as a treatment for cardiovascular diseases. It's like a camel discovering a new oasis in the vast desert of medical research, finding a potential solution to a widespread health problem. The study investigates the pharmacological effects and potential therapeutic applications of DMF in the treatment of cardiovascular diseases.

A New Oasis: DMF's Potential for Cardiovascular Health

This research highlights the potential of DMF as a treatment for cardiovascular disease, due to its anti-inflammatory and vasculoprotective properties. It's like finding a refreshing oasis in the middle of a parched desert, offering relief and potential healing for a major health concern. The study emphasizes the need for further research to fully understand DMF's effects on cardiovascular health and to confirm its safety and efficacy in large clinical trials.

A Camel's Guide to Heart Health: Lifestyle and Prevention

Maintaining a healthy lifestyle, including a balanced diet, regular exercise, and managing stress, is crucial for preventing and managing cardiovascular disease. It's like a camel preparing for a long journey across the desert, ensuring its health and well-being to avoid the dangers of the environment. If you have any concerns about your heart health, consult a healthcare professional for proper assessment and guidance.

Dr.Camel's Conclusion

This research explores the promising potential of DMF as a therapeutic agent for cardiovascular diseases. It emphasizes the importance of ongoing research and innovation in seeking new and effective treatments for this widespread condition. The findings offer a glimmer of hope in the desert of cardiovascular health, suggesting potential avenues for improving treatment and management of heart diseases.

Date :
  1. Date Completed n.d.
  2. Date Revised 2022-07-16
Further Info :

Pubmed ID

35631325

DOI: Digital Object Identifier

PMC9143321

SNS
PICO Info
in preparation
Languages

English

Positive IndicatorAn AI analysis index that serves as a benchmark for how positive the results of the study are. Note that it is a benchmark and requires careful interpretation and consideration of different perspectives.

This site uses cookies. Visit our privacy policy page or click the link in any footer for more information and to change your preferences.