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Comparison of salbutamol and ephedrine in oral bronchodilator combinations with theophylline and hydroxyzine: their effects on asthmatics.

Author: AlankoK, LahdensuoA

Clinical TrialA clinical trial is a planned study conducted on humans to evaluate the efficacy and safety of pharmaceuticals, medical devices, and treatment methods. It aims to explore the possibilities of new treatments and improve the health of patients.
Comparative StudyResearch that compares multiple groups/interventions to determine differences/similarities in outcomes/characteristics.
Controlled Clinical TrialA clinical trial that evaluates the effectiveness of a treatment by comparing a group that receives the intervention with a group that receives a placebo or standard treatment.
Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.
Randomized Controlled TrialA clinical trial that randomly assigns participants to treatment and control groups to evaluate the effects of an intervention.

Overview

Three antiasthamatic bronchodilator combinations were compared in a double-blind cross-over trial in patients with asthma. All combinations tested were more effective than placebo, with the most potent sympathomimetic drug in the combination having the greatest therapeutic effect.
Paper Details　
Original Abstract of the Article :
The efficacies of three antiasthamatic bronchodilator combinations were compared using data obtained from sixteen patients. During the trial the patients measured their peak expiratory flow (PEF) every day at 7.00 a.m., 10.00 a.m. and 9.30 pm. Six patients also measured their PEF at 1.30 a.m. The fr...See full text at original site
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引用元：
https://pubmed.ncbi.nlm.nih.gov/356718

データ提供：米国国立医学図書館（NLM）

Asthmatic Relief: Finding the Right Combination in the Desert of Respiratory Distress

Asthma is a chronic respiratory condition that can significantly impact a person's quality of life. Asthmatic attacks, like a sudden sandstorm, can cause difficulty breathing, wheezing, and coughing. This study, like a journey through a desert searching for a safe haven, investigated the effectiveness of different combinations of bronchodilator medications in managing asthma symptoms.

The Right Combination for Relief

The study found that adding salbutamol or ephedrine to a combination of theophylline and hydroxyzine increased the therapeutic effect, providing greater relief from asthma symptoms. However, the study also found that increasing the potency of the sympathomimetic drug in the combination increased the risk of side effects.

Navigating the Desert of Asthma

This research underscores the importance of finding the right balance between efficacy and side effects when managing asthma. The study provides valuable insights into the potential benefits and risks of different drug combinations, helping clinicians to tailor treatment plans to meet the specific needs of each patient.

Dr.Camel's Conclusion

The study highlights the importance of finding the right balance between efficacy and side effects when managing asthma, providing valuable insights into the potential benefits and risks of different drug combinations.

Date :
  1. Date Completed 1978-10-27
  2. Date Revised 2013-11-21
Further Info :

Pubmed ID

356718

DOI: Digital Object Identifier

356718

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Article Analysis
・Side Effects of albuterol oral inhalation
SNS
PICO Info
in preparation
Languages

English

Positive IndicatorAn AI analysis index that serves as a benchmark for how positive the results of the study are. Note that it is a benchmark and requires careful interpretation and consideration of different perspectives.

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