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Effects of oral treatment with chondroitin sulfate and glucosamine in an experimental model of metacarpophalangeal osteoarthritis in horses.
Author: AgresteFernanda Rodrigues, BaccarinRaquel Yvonne Arantes, FülberJoice, MarsigliaMarília Ferrari, SeidelSarah Raphaela Torquato, SoteloEric Danilo Pauls, YamadaAna Lucia Miluzzi, da SilvaLuis Claudio Lopes Correia, do Prado VendruscoloCynthia
Original Abstract of the Article :
Combined chondroitin sulfate (CS) and glucosamine (GlcN) has been widely used in oral formulations to prevent and treat osteoarthritis. CS is effective for controlling pain in osteoarthritic patients, whereas GlcN can stimulate glycosaminoglycan synthesis, thus reducing extracellular matrix degradat...See full text at original site
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引用元：
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9178899/
データ提供：米国国立医学図書館（NLM）
Chondroitin Sulfate and Glucosamine: Effects on Osteoarthritis in Horses
Osteoarthritis (OA), a degenerative joint disease, affects not only humans but also our equine friends. This study explores the potential benefits of oral treatment with chondroitin sulfate (CS) and glucosamine (GlcN) in managing OA in horses. The researchers used an experimental model of metacarpophalangeal OA in horses to investigate the effects of CS and GlcN on the progression of the disease. They aimed to determine whether this combination could effectively treat or modulate OA in this animal model.
Investigating the Effects of CS and GlcN on Osteoarthritis in Horses
The study found that oral treatment with CS and GlcN had a positive effect on the progression of OA in horses. The researchers observed improvements in physical, ultrasonographic, and radiographic examinations, as well as in synovial fluid biomarkers. These findings suggest that CS and GlcN may help manage OA symptoms and potentially slow down disease progression in horses.
Understanding Osteoarthritis and Potential Treatment Options
This study contributes to our understanding of OA in horses and the potential therapeutic benefits of CS and GlcN. The findings encourage further research to validate the effectiveness of this treatment approach and determine its long-term impact on OA management in horses. By exploring various treatment options, we can strive to improve the quality of life for our equine companions and help them navigate the challenges of OA.
Dr. Camel's Conclusion
Just like a camel's strong legs carry it across the desert, healthy joints are vital for the well-being of horses. This study explores the potential of CS and GlcN in managing OA in horses, highlighting the importance of finding effective treatments to support their mobility and quality of life. By embracing research and exploring new approaches, we can strive to ensure that our equine companions experience a comfortable and fulfilling life.
Date :
- Date Completed 2022-06-13
- Date Revised 2022-07-16
Further Info :
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