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Proposed European Competence Network on Mastocytosis-American Initiative in Mast Cell Diseases (ECNM-AIM) Response Criteria in Advanced Systemic Mastocytosis.
Author: AkinCem, ArockMichel, BonadonnaPatrizia, BrockowKnut, ButterfieldJoseph H, CarterMelody C, CastellsMariana, ElberinkHanneke Oude, GeorgeTracy I, GotlibJason, HartmannKarin, HermineOlivier, HoermannGregor, HornyHans-Peter, LyonsJonathan J, LübkeJohannes, MetcalfeDean D, NiedoszytkoMarek, OrfaoAlberto, RadiaDeepti H, ReiterAndreas, SchwaabJuliana, SchwartzLawrence B, ShomaliWilliam, SiebenhaarFrank, SotlarKarl, SperrWolfgang R, TriggianiMassimo, UstunCelalettin, ValentPeter, ZanottiRoberta, Álvarez-TwoseIvan
Original Abstract of the Article :
Advanced systemic mastocytosis (AdvSM) is characterized by the presence of KIT D816V and other somatic mutations (eg, in SRSF2, ASXL1, and RUNX1) in 95% and 60% to 70% of patients, respectively. The biological and clinical consequences of AdvSM include multilineage involvement (eg, associated hemato...See full text at original site
Dr.Camel's Paper Summary Blogラクダ博士について
ラクダ博士は、Health Journal が論文の内容を分かりやすく解説するために作成した架空のキャラクターです。
難解な医学論文を、専門知識のない方にも理解しやすいように、噛み砕いて説明することを目指しています。
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* ラクダ博士は架空のキャラクターであり、実際の医学研究者や医療従事者とは一切関係がありません。
* 解説の内容は Health Journal が独自に解釈・作成したものであり、原論文の著者または出版社の見解を反映するものではありません。
引用元:
https://doi.org/10.1016/j.jaip.2022.05.034
データ提供:米国国立医学図書館(NLM)
Navigating the Desert of Mastocytosis
Mastocytosis, a rare disorder characterized by the overgrowth of mast cells, is like a hidden oasis in the desert, both beautiful and potentially dangerous. This article, published in the journal Blood, explores the development of response criteria for advanced systemic mastocytosis (AdvSM), a severe form of mastocytosis that can affect various organs and systems.
Mapping the Terrain: Response Criteria for Mastocytosis
The authors discuss the evolution of response criteria for AdvSM, comparing it to a map that helps navigate the complexities of the disease. They recognize the need for refined criteria to accurately assess treatment response and track patient outcomes.
Finding the Oasis: Improved Treatment Strategies
This research, like a beacon in the desert, sheds light on the importance of developing robust response criteria to guide treatment decisions for AdvSM. By accurately measuring treatment efficacy and monitoring patient progress, clinicians can optimize treatment strategies and improve patient outcomes.
Dr. Camel's Conclusion
This article underscores the importance of accurate assessment in the treatment of AdvSM. By developing and refining response criteria, clinicians can better navigate the challenging terrain of this complex disease, offering hope for patients seeking relief from its debilitating symptoms.
Date :
- Date Completed 2022-08-16
- Date Revised 2022-09-16
Further Info :
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