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Porto-pulmonary arterial hypertension: Translation of pathophysiological concepts to the bedside.

Author: BadagliaccaRoberto, CaterinaRaffaele De, MadonnaRosalinda, MazzolaMatteo

Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.
ReviewAn article that critically examines existing research on a particular topic and summarizes the current state of knowledge in the field.

Overview

Porto-pulmonary arterial hypertension (PoPAH) is a form of pulmonary arterial hypertension (PAH) affecting patients with cirrhosis. PoPAH patients have a worse survival than those with other PAH forms despite favorable hemodynamics. This review discusses the pathophysiology and management of PoPAH and reports a case vignette of a patient with PoPAH due to hepatorenal polycystic disease.
Paper Details　
Original Abstract of the Article :
Porto-pulmonary arterial hypertension (PoPAH) is a form of pulmonary arterial hypertension (PAH) that affects patients with cirrhosis, and - to a lesser extent - patients with non-cirrhotic liver diseases. Compared with other forms of PAH, PoPAH is more prevalent in male, in older subjects, and is c...See full text at original site
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引用元：
https://doi.org/10.1016/j.vph.2022.107022

データ提供：米国国立医学図書館（NLM）

Porto-pulmonary Arterial Hypertension: Translation of Pathophysiological Concepts to the Bedside

This study embarks on a journey through the complex landscape of cardiopulmonary medicine, exploring the intricate mechanisms and treatment options for a rare but serious condition known as porto-pulmonary arterial hypertension (PoPAH). PoPAH is a form of pulmonary hypertension that affects individuals with liver disease, primarily cirrhosis. The researchers delve into the unique pathophysiological characteristics of PoPAH and its distinctive clinical presentation compared to other forms of pulmonary hypertension. They also examine the challenges of treating PoPAH, emphasizing the need for tailored therapeutic approaches.

PoPAH: A Complex Challenge in Pulmonary Hypertension

This study sheds light on the unique challenges of treating PoPAH, a challenging form of pulmonary hypertension linked to liver disease. The research highlights the distinct characteristics of PoPAH, emphasizing the need for specialized diagnostic and therapeutic approaches. The researchers underscore the importance of translating scientific knowledge into effective bedside management strategies for patients with this complex condition.

Navigating the Labyrinth of PoPAH

Imagine a patient with PoPAH as a weary traveler lost in a labyrinth of medical complexities. The researchers, like expert guides, provide a roadmap for navigating this challenging terrain. They emphasize the importance of understanding the specific characteristics of PoPAH and tailoring treatment strategies to address its unique challenges. This research provides a beacon of hope for patients with PoPAH, offering guidance and support for their journey toward improved health.

Dr.Camel's Conclusion

This study is a testament to the power of collaborative research and the importance of translating scientific discoveries into real-world applications. The researchers' focus on understanding and managing PoPAH is a crucial step towards improving the lives of patients with this rare but serious condition. This research serves as a reminder that even in the most challenging medical situations, knowledge, compassion, and innovation can guide us towards better outcomes.
Date :
  1. Date Completed 2022-09-20
  2. Date Revised 2022-09-27
Further Info :

Pubmed ID

35738494

DOI: Digital Object Identifier

10.1016/j.vph.2022.107022

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Languages

English

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